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  2. Human anti-mouse antibody - Wikipedia

    en.wikipedia.org/wiki/Human_anti-mouse_antibody

    Doctors have termed this the “HAMA response,” referring to the development of Human Anti-Mouse Antibodies (HAMA). The HAMA response is essentially an allergic reaction to the mouse antibodies that can range from a mild form, like a rash, to a more extreme and life-threatening response, such as kidney failure. HAMA can also decrease the ...

  3. Heterophile antibody - Wikipedia

    en.wikipedia.org/wiki/Heterophile_antibody

    Heterophile antibodies can cause significant interference in any immunoassay. [3] The presence of a heterophile antibody is characterized by broad reactivity with antibodies of other animal species (which are often the source of the assay antibodies). Such antibodies are commonly referred to as human anti-animal antibodies (HAAA).

  4. Hook effect - Wikipedia

    en.wikipedia.org/wiki/Hook_effect

    The antibody that fails to react is known as the blocking antibody and prevents the precipitating antibody from binding to the antigens. Thus the proper precipitation reaction does not take place. However, when the serum is diluted, the blocking antibody is as well and its concentration decreases enough for the proper precipitation reaction to ...

  5. Immunoglobulin class switching - Wikipedia

    en.wikipedia.org/wiki/Immunoglobulin_class_switching

    Mechanism of class-switch recombination that allows isotype switching in activated B cells. Immunoglobulin class switching, also known as isotype switching, isotypic commutation or class-switch recombination (CSR), is a biological mechanism that changes a B cell's production of immunoglobulin from one type to another, such as from the isotype IgM to the isotype IgG. [1]

  6. Minretumomab - Wikipedia

    en.wikipedia.org/wiki/Minretumomab

    Minretumomab (CC49) is a mouse monoclonal antibody [1] that was designed for the treatment of cancers that express the TAG-72 antigen. This includes breast, colon, lung, and pancreatic cancers. [2] [3] Apparently, it never got past Phase I clinical trials for this purpose. [4]

  7. Minnesota Parents Who Locked Their Kids in Cages for ‘Their ...

    www.aol.com/minnesota-parents-locked-kids-cages...

    A Minnesota couple has reportedly been sentenced to four years after they locked their children in cages for "their safety." Benjamin and Christina Cotton from Red Wing, were sentenced by a ...

  8. Anti-thymocyte globulin - Wikipedia

    en.wikipedia.org/wiki/Anti-thymocyte_globulin

    The first report of immunizing an animal of one species (guinea pig) against the immune cells of another species (mouse lymphocytes) was by Élie Metchnikoff in 1899. He reported injecting cells recovered from mouse lymph nodes into Guinea pigs and waiting for the immunization to result in the accumulation of anti-mouse antibodies in the Guinea pig blood.

  9. Pregnant Woman Reportedly Stabbed 14 Times by Pizza Delivery ...

    www.aol.com/pregnant-woman-reportedly-stabbed-14...

    A pregnant woman is recovering in the hospital after she was stabbed multiple times by a pizza delivery driver over the size of her tip, according to reports. The incident happened on Sunday, Dec ...

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