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A bipolar neuron, or bipolar cell, is a type of neuron characterized by having both an axon and a dendrite extending from the soma (cell body) in opposite directions. These neurons are predominantly found in the retina and olfactory system. [ 1 ]
Multipolar neurons are composed of one axon and many dendritic trees. Pyramidal cells are multipolar cortical neurons with pyramid-shaped cell bodies and large dendrites that extend towards the surface of the cortex (apical dendrite). Bipolar neurons have two main dendrites at opposing ends of the cell body.
Bipolar cells receive synaptic input from either rods or cones, or both rods and cones, though they are generally designated rod bipolar or cone bipolar cells. There are roughly 10 distinct forms of cone bipolar cells, however, only one rod bipolar cell, due to the rod receptor arriving later in the evolutionary history than the cone receptor ...
Diffuse bipolars can take signals from up to 50 rods or can be a flat cone form and take signals from seven cones. The bipolar cells corresponds to the intermediary cells between the touch and heat receptors on the skin and the medulla or spinal cord. [1]
The main loci of neuroimaging and neuropathological findings in bipolar have been proposed to constitute dysfunction in a "visceromotor" network, composed of the medial prefrontal cortex (mPFC), anterior cingulate cortex (ACC), orbitofrontal cortex (OFC), hippocampus, amygdala, hypothalamus, striatum and thalamus. [32]
The olfactory receptor neurons are sensory neurons of the olfactory epithelium. They are bipolar neurons and their apical poles express odorant receptors on non-motile cilia at the ends of the dendritic knob, [4] which extend out into the airspace to interact with odorants.
Bipolar disorder can also involve depressive episodes, which have the same symptoms that people with major depressive disorder experience. Symptoms of a depressive episode can include:
It receives visual information from photoreceptors via two intermediate neuron types: bipolar cells and retina amacrine cells. Retina amacrine cells, particularly narrow field cells, are important for creating functional subunits within the ganglion cell layer and making it so that ganglion cells can observe a small dot moving a small distance. [1]
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