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2-Octyl cyanoacrylate is a cyanoacrylate ester typically used as a wound closure adhesive (under the brand name Dermabond). [1] It is closely related to octyl cyanoacrylate . The use of 2-octyl cyanoacrylate was approved in 1998; offered as an alternative to stitches, sutures, and or adhesive strips.
A dermal adhesive (or skin glue) is a glue used to close wounds in the skin as an alternative to sutures, staples, or clips. Glued closure results in less scarring and is less prone to infection than sutured or stapled closure. There is also no residual closure to remove, so follow-up visits for removal are not required.
Cyanoacrylate adhesives may adhere to body parts, and injuries may occur when parts of the skin are torn off. [27] [28] Without force, however, the glue will spontaneously separate from the skin in time (up to four days). The glue can also cause chemical burns, and exposed skin should be washed with soap and warm water. [29]
The medical applications of butyl cyanoacrylate include its use as an adhesive for lacerations of the skin, [5] and in the treatment of bleeding from vascular structures. Butyl cyanoacrylate has been used to treat arteriovenous malformations [ 6 ] by application of the glue into the abnormality through angiography .
Liquid bandage is typically a polymer dissolved in a solvent (commonly water or an alcohol), sometimes with an added antiseptic and local anesthetic, although the alcohol in some brands may serve the same purpose. [1] These products protect the wound by forming a thin film of polymer when the carrier evaporates. [1]
Compound Benzoin Tincture is often applied to skin under an adhesive bandage. It protects the skin from allergy to the adhesive and makes the bandage adhere longer. [5] It is also used by athletes for its reputation of toughening skin. Orthopedists often apply it under a cast, because it protects the skin and diminishes itching.
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The drug layer is a liquid compartment containing a drug solution or suspension separated by the adhesive layer. The drug reservoir is totally encapsulated in a shallow compartment molded from a drug-impermeable metallic plastic laminate, with a rate-controlling membrane made of a polymer like vinyl acetate on one surface. [ 24 ]