Search results
Results from the WOW.Com Content Network
Most primary and secondary perfluoroalcohols are unstable, for example trifluoromethanol eliminates hydrogen fluoride, forming carbonyl fluoride. [2] This reaction is reversible. [3] CF 3 OH → COF 2 + HF. Stable perfluorinated alcohols include nonafluoro-tert-butyl alcohol ((CF 3) 3 COH) and pentafluorophenol (C 6 F 5 OH).
PhN=N-N(CH 2) 5 + 2 HF → PhF + N 2 + [(CH 2) 5 NH 2]F. Historical note: in Wallach's era, the element fluorine was symbolized with "Fl". Thus, his procedure is subtitled "Fluorbenzol, C 6 H 5 Fl". [1] On the laboratory scale, PhF is prepared by the thermal decomposition of the benzenediazonium tetrafluoroborate: PhN 2 BF 4 → PhF + BF 3 + N 2
This reagent can be used, e.g. in the reaction with carbon dioxide to prepare benzoic acid. [4] Other methods involve palladium-catalyzed coupling reactions, such as the Suzuki reaction. Bromobenzene is used as a precursor in the manufacture of phencyclidine.
Benzyl bromide is an organic compound with the formula C 6 H 5 CH 2 Br. The molecule consists of a benzene ring substituted with a bromomethyl group. It is a colorless liquid with lachrymatory properties. The compound is a reagent for introducing benzyl groups. [3] [4]
All three have been synthesized by various routes: 1-Bromo-2-chlorobenzene: from 2-chloroaniline, via diazotization followed by a Sandmeyer reaction [1]; 1-Bromo-3-chlorobenzene: by (3-chlorophenyl)trimethylgermanium by electrophilic substitution [2] [better source needed]
4-Fluorobromobenzene is synthesized via bromination of fluorobenzene in the presence of a Lewis acid catalyst such as iron(III) bromide or aluminium tribromide. [2]4-Bromofluorobenzene is regarded by the Toxic Substances Control Act as a high production volume chemical, that is, a chemical that 1 million pounds (about 500 tonnes) per year is either produced in or imported to the United States.
2-Phenethyl bromide (C 6 H 5 CH 2 CH 2 Br) is produced via this route from styrene. Hydrogen bromide can also be used to convert alcohols to alkyl bromides. This reaction, that must be done under low temperature conditions, is employed in the industrial synthesis of allyl bromide: HOCH 2 CH=CH 2 + HBr → BrCH 2 CH=CH 2 + H 2 O
tert-Butyl bromide (also referred to as 2-bromo-2-methylpropane) is an organic compound with the formula Me 3 CBr (Me = methyl). The molecule features a tert-butyl group attached to a bromide substituent. This organobromine compound is used as a standard reagent in synthetic organic chemistry. It is a colorless liquid.