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In humans, the kidneys are two reddish-brown bean-shaped blood-filtering organs [1] that are a multilobar, multipapillary form of mammalian kidneys, usually without signs of external lobulation. [2] [3] They are located on the left and right in the retroperitoneal space, and in adult humans are about 12 centimetres (4 + 1 ⁄ 2 inches) in length.
This illustration demonstrates the normal kidney physiology, including the Proximal Convoluted Tubule (PCT), Loop of Henle, and Distal Convoluted Tubule (DCT). It also includes illustrations showing where some types of diuretics act, and what they do. Renal physiology (Latin renes, "kidneys") is the study of the physiology of the kidney.
The kidneys in mammals are usually bean-shaped [4] or externally lobulated. [5] They are located behind the peritoneum (retroperitoneally) [6] on the back wall of the body. [7] The typical mammalian kidney consists of a renal capsule, a peripheral cortex, an internal medulla, one or more renal calyces, and a renal pelvis. [7]
The first step in urine formation is the filtration of blood in the kidneys. In a healthy human, the kidney receives between 12 and 30% of cardiac output, but it averages about 20% or about 1.25 L/min. The basic structural and functional unit of the kidney is the nephron.
This diagram is a retouched picture, which means that it has been digitally altered from its original version. Modifications: translated svg file using png file. text objects are preserved as text objects for ease of future editing/translation. The original can be viewed here: Kidney nephron molar transport diagram.png: .
The kidneys in reptiles are located mainly in the caudal part (away from the head) of the abdominal cavity [49] [50] or retroperitoneally (behind the peritoneum) in the pelvic cavity in the case of lizards. [49] Reptile kidneys are commonly elongated [51] with color ranging from light to dark brown. [52]
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Glomerular filtration rate (GFR) is the volume of fluid filtered from the renal (kidney) glomerular capillaries into the Bowman's capsule per unit time. [4] Central to the physiologic maintenance of GFR is the differential basal tone of the afferent (input) and efferent (output) arterioles (see diagram).