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Vitamin C megadosage is a term describing the consumption or injection of vitamin C (ascorbic acid) in doses well beyond the current United States Recommended Dietary Allowance of 90 milligrams per day, and often well beyond the tolerable upper intake level of 2,000 milligrams per day. [1]
Vitamin C supplements among other dietary supplements at a US drug store. Vitamin C has a definitive role in treating scurvy, which is a disease caused by vitamin C deficiency. Beyond that, a role for vitamin C as prevention or treatment for various diseases is disputed, with reviews often reporting conflicting results.
Dehydroascorbic acid has been used as a vitamin C dietary supplement. [9] As a cosmetic ingredient, dehydroascorbic acid is used to enhance the appearance of the skin. [10] It may be used in a process for permanent waving of hair [11] and in a process for sunless tanning of skin. [12]
Sodium ascorbate is one of a number of mineral salts of ascorbic acid (vitamin C). The molecular formula of this chemical compound is C 6 H 7 NaO 6. As the sodium salt of ascorbic acid, it is known as a mineral ascorbate. It has not been demonstrated to be more bioavailable than any other form of vitamin C supplement. [2]
In the 1930s and 1940s, some scientific and clinical evidence suggested that there might be beneficial uses of vitamins C, E, and niacin in large doses. Beginning in the 1930s in Canada , a megadose vitamin E therapy for cardiovascular and circulatory complaints was developed by Evan Shute and colleagues, named the "Shute protocol". [ 15 ]
Years-long contract fights at media companies came to a head in 2024, leading to walk-outs by unions from the New York Times, NBC and Forbes.
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