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Targeted alpha-particle therapy (or TAT) is an in-development method of targeted radionuclide therapy of various cancers. It employs radioactive substances which undergo alpha decay to treat diseased tissue at close proximity. [1] It has the potential to provide highly targeted treatment, especially to microscopic tumour cells.
Alpha radiation is a nuclear phenomenon in which a heavy radionuclide emits an energetic alpha particle (consisting of two protons and two neutrons) and transmutes to a different radionuclide. The emitted alpha particle has a range in tissue of only 40-90 microns, which minimizes collateral damage when used for treatment purposes.
Androgen deprivation therapy (ADT), also called androgen ablation therapy or androgen suppression therapy, is an antihormone therapy whose main use is in treating prostate cancer. Prostate cancer cells usually require androgen hormones , such as testosterone , to grow.
The use of radium-223 to treat metastatic bone cancer relies on the ability of alpha radiation from radium-223 and its short-lived decay products to kill cancer cells. Radium is preferentially absorbed by bone by virtue of its chemical similarity to calcium, with most radium-223 that is not taken up by the bone being cleared, primarily via the ...
When paired with alpha or beta emitters, therapy can be achieved, as in PRRT. [4] The current generation of PRRT targets somatostatin receptors, with a range of analogue materials such as octreotide and other DOTA compounds. These are combined with indium-111, lutetium-177 or yttrium-90 for treatment.
A meta-analysis of several different hair loss treatments found low-level light therapy to be effective at promoting hair growth in men with androgenetic alopecia.
Photodynamic therapy (PDT) is an emerging focal therapy for the treatment of prostate cancer, offering a minimally invasive alternative to traditional treatments. PDT involves the administration of a photosensitizing agent , which is activated by exposure to a specific type of light.
Men can do the same,” says Alex Robboy, a sex therapist in Philadelphia. Essentially, kegel exercises are a way of contracting the muscles of the pelvic floor, which give you greater control and ...