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Vancomycin is usually given intravenously, as an infusion, and can cause tissue necrosis and phlebitis at the injection site if given too rapidly. Pain at the site of injection is indeed a common adverse event. One of the side effects is red man syndrome, an idiosyncratic reaction to bolus caused by histamine release.
A zoster vaccine is a vaccine that reduces the incidence of herpes zoster (shingles), a disease caused by reactivation of the varicella zoster virus, which is also responsible for chickenpox. [8] Shingles provokes a painful rash with blisters, and can be followed by chronic pain ( postherpetic neuralgia ), as well as other complications.
Vancomycin is a glycopeptide antibiotic medication used to treat certain bacterial infections. [7] It is administered intravenously (injection into a vein) to treat complicated skin infections, bloodstream infections, endocarditis, bone and joint infections, and meningitis caused by methicillin-resistant Staphylococcus aureus. [8]
The vaccine reduced rates of persistent, severe pain after shingles by 66% in people who contracted shingles despite vaccination. [59] Vaccine efficacy was maintained through four years of follow-up. [59] It has been recommended that people with primary or acquired immunodeficiency should not receive the live vaccine. [59]
The herpes zoster vaccine is recommended for prevention in those over the age of 50. [2] HZO is the second most common manifestation of shingles, the first being involvement of skin of the thorax. [citation needed] Shingles affects up to one half million people in the United States per year, of which 10% to 25% is HZO. [1] [3]
It belongs to the same class as vancomycin, the most widely used and one of the treatments available to people infected with methicillin-resistant Staphylococcus aureus (MRSA). [ 7 ] Dalbavancin is a semisynthetic lipoglycopeptide that was designed to improve upon the natural glycopeptides vancomycin and teicoplanin . [ 8 ]
A drug of last resort (DoLR), also known as a heroic dose, [1] is a pharmaceutical drug which is tried after all other drug options have failed to produce an adequate response in the patient. Drug resistance , such as antimicrobial resistance or antineoplastic resistance , may make the first-line drug ineffective, especially in case of ...
The zoster vaccine Shingrix provides around 90% protection from postherpetic neuralgia, and has been used in many countries since 2017. The earlier vaccine Zostavax provides lesser protection against shingles, and PHN. [6] The varicella vaccine is approved for infants to prevent chickenpox, which also protects against PHN from a herpes zoster ...