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Clobetasol is believed to work by activating steroid receptors. [8] Clobetasol propionate was patented in 1968 and came into medical use in 1978. [13] It is available as a generic medication. [10] In 2022, it was the 156th most commonly prescribed medication in the United States, with more than 3 million prescriptions. [14] [15]
Clobetasol propionate 0.05%; Diflucortolone valerate 0.3% (not available in the US) Fluocinonide 0.1%; Flurandrenolide 4 mcg/cm 2; Halobetasol propionate 0.05%;
Clobetasol propionate 0.05% (Dermovate) Betamethasone dipropionate 0.25% (Diprolene) ... (Capex shampoo, Dermasmooth) Desonide 0.05% (DesOwen cream, lotion) Class VII
Clobetasol is a synthetic glucocorticoid corticosteroid. A propionate ester of clobetasol, clobetasol propionate , has also been marketed, and is far more widely used in comparison. [ 2 ] [ 3 ]
In dermatology, topical clobetasone butyrate helps to reduce the itchiness and erythema associated with eczema and dermatitis. [5]In ophthalmology, clobetasone butyrate 0.1% eye drops have been shown to be safe and effective in the treatment of dry eyes in Sjögren syndrome.
Ulobetasol propionate is usually supplied as a 0.05% topical cream. [1] Ulobetasol is the strongest topical steroid available. [citation needed] It is also sold with tazarotene with 0.01% halobetasol and 0.045% tazarotene as a lotion branded as Duobrii (Bausch Health). It is available as a generic medication. [5]
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