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Sweat testing makes use of the fact that cystic fibrosis patients have defective sweat glands. [2] Sweat glands produce sweat through a well understood process of secretion and reabsorption of sodium chloride (salt). Secretion entails the movement of salt and water from sweat gland cells into the sweat duct.
Sweat diagnostics is an emerging non-invasive technique used to provide insights to the health of the human body. Common sweat diagnostic tests include testing for cystic fibrosis [1] and illicit drugs. [2] Most testing of human sweat is in reference to the eccrine sweat gland which in contrast to the apocrine sweat gland, has a lower ...
Iontophoresis is useful in laboratory experiments, especially in neuropharmacology. [5] Transmitter molecules naturally pass signals between neurons.By microelectrophoretic techniques, including microiontophoresis, neurotransmitters and other chemical agents can be artificially administered very near living and naturally functioning neurons, the activity of which can be simultaneously recorded.
Sudomotor function refers to the autonomic nervous system control of sweat gland activity in response to various environmental and individual factors. Sweat production is a vital thermoregulatory mechanism used by the body to prevent heat-related illness as the evaporation of sweat is the body’s most effective method of heat reduction and the only cooling method available when the air ...
Hyperhidrosis is a medical condition in which a person exhibits excessive sweating, [1] [2] more than is required for the regulation of body temperature. [3] Although it is primarily a physical burden, hyperhidrosis can deteriorate the quality of life of the people who are affected from a psychological, emotional, and social perspective. [4]
See also sweat gland, eccrine sweat gland and Autonomic nervous system.. The ESC measurement relies on the particularities of the outer-most layer of the human skin, the stratum corneum (SC), which consists of a lipid corneocyte matrix crossed by skin appendages (sweat glands and their follicles) as described in Electrical properties of skin at moderate voltages: contribution of appendageal ...
If gene testing finds one mutation they will then have a sweat test to help confirm the diagnosis. Sweat testing is more likely to be equivocal in infants and typically not attempted in those under 5 kg. If sweat test is positive more comprehensive gene testing is considered. If two mutations are found they are diagnosed with CF.
The amount of sweat glands varies across the human body, being highest in hand and foot regions (200–600 sweat glands per cm 2). [19] The response of the skin and muscle tissue to external and internal stimuli can cause the conductance to vary by several microsiemens .