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The prefrontal cortex has been defined based on cytoarchitectonics by the presence of a cortical granular layer IV.It is not entirely clear who first used this criterion. Many of the early cytoarchitectonic researchers restricted the use of the term prefrontal to a much smaller region of cortex including the gyrus rectus and the gyrus rostralis (Campbell, 1905; G. E. Smith, 1907; Brodmann ...
Not all animals have neurons; Trichoplax and sponges lack nerve cells altogether. Neurons may be packed to form structures such as the brain of vertebrates or the neural ganglions of insects . The number of neurons and their relative abundance in different parts of the brain is a determinant of neural function and, consequently, of behavior.
So despite the nidopallium and prefrontal cortex having evolved separately (an educated assumption), both have achieved similar functions of higher order thought processes via convergent evolution, as a result of influences at the molecular level. The nidopallium is also heavily innervated by dopaminergic neurons from the direction of the ...
The human cerebral cortex is also characterized by a higher gradient of retinoic acid in the prefrontal cortex, leading to higher prefrontal cortex volume. All these differential gene expression lead to higher proliferation of the neural progenitors leading to more neurons in the human cerebral cortex.
Damage to Broca's area is commonly associated with telegraphic speech made up of content vocabulary. For example, a person with Broca's aphasia may say something like, "Drive, store. Mom." meaning to say, "My mom drove me to the store today." Therefore, the content of the information is correct, but the grammar and fluidity of the sentence is ...
The orbitofrontal cortex (OFC) is a prefrontal cortex region in the frontal lobes of the brain which is involved in the cognitive process of decision-making. In non-human primates it consists of the association cortex areas Brodmann area 11 , 12 and 13 ; in humans it consists of Brodmann area 10 , 11 and 47 .
The VP, in turn, projects to the medial dorsal nucleus of the dorsal thalamus, which projects to the prefrontal cortex as well as back to the ventral and to dorsal striatum. Other efferents from the nucleus accumbens include connections with the tail of the ventral tegmental area, [24] substantia nigra, and the reticular formation of the pons. [1]
Micrograph showing a von Economo neuron of the cingulate. HE-LFB stain.. Von Economo neurons, also called spindle neurons, are a specific class of mammalian cortical neurons characterized by a large spindle-shaped soma (or body) gradually tapering into a single apical axon (the ramification that transmits signals) in one direction, with only a single dendrite (the ramification that receives ...