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  2. Loop diuretic - Wikipedia

    en.wikipedia.org/wiki/Loop_diuretic

    The biological half-life of furosemide is limited by absorption from the gastrointestinal tract into the bloodstream. The apparent half-life of its excretion is higher than the apparent half-life of absorption via the oral route. Therefore, furosemide taken intravenously is twice as potent as an equivalent dose taken orally. [6]

  3. Equianalgesic - Wikipedia

    en.wikipedia.org/wiki/Equianalgesic

    An equianalgesic chart can be a useful tool, but the user must take care to correct for all relevant variables such as route of administration, cross tolerance, half-life and the bioavailability of a drug. [5] For example, the narcotic levorphanol is 4–8 times stronger than morphine, but also has a much longer half-life. Simply switching the ...

  4. Chlortalidone - Wikipedia

    en.wikipedia.org/wiki/Chlortalidone

    As with other thiazide diuretics, chlortalidone crosses the placenta and is excreted in breast milk. [49] Chlortalidone may suppress lactation, and has been used for this indication. Due to its long half-life, chlortalidone may accumulate in newborns via breast milk, despite receiving only about 6% of the maternal weight-adjusted dose. [50]

  5. Hydrochlorothiazide - Wikipedia

    en.wikipedia.org/wiki/Hydrochlorothiazide

    Hydrochlorothiazide, sold under the brand name Hydrodiuril among others, is a diuretic medication used to treat hypertension and swelling due to fluid build-up. [4] Other uses include treating diabetes insipidus and renal tubular acidosis and to decrease the risk of kidney stones in those with a high calcium level in the urine. [4]

  6. Donald Trump mocked Canadian Prime Minister Justin Trudeau after his top minister’s surprise resignation following a clash on how to handle the president-elect’s looming tariffs.

  7. Retirement expert: The need for unpaid caregivers is 'about ...

    www.aol.com/finance/retirement-expert-unpaid...

    According to Kolluri, life expectancy at birth has increased by about 17 years since Social Security's inception. At the same time, he noted, 1 in 5 adults provide uncompensated care and spend an ...

  8. Yahoo co-founder Jerry Yang: Masayoshi Son is recasting ... - AOL

    www.aol.com/finance/yahoo-co-founder-jerry-yang...

    SoftBank billionaire Masayoshi Son has pledged to invest $100 billion in the US over the next four years. Masa's longtime friend and Yahoo co-founder Jerry Yang weighs in on the pledge.

  9. Bumetanide - Wikipedia

    en.wikipedia.org/wiki/Bumetanide

    Bumetanide is a loop diuretic and works by decreasing the reabsorption of sodium by the kidneys. The main difference between bumetanide and furosemide is in their bioavailability and potency. About 60% of furosemide is absorbed in the intestine, and there are substantial inter- and intraindividual differences in bioavailability (range 10-90%).