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  2. Gleason grading system - Wikipedia

    en.wikipedia.org/wiki/Gleason_grading_system

    Gleason score 3+4=7 (prognostic grade group II) indicating the majority is pattern 3; Gleason score 4+3=7 (prognostic grade group III) where pattern 4 is dominant; [6] Gleason score 4+4=8 (prognostic grade group IV); Gleason scores 9-10 (prognostic grade group V). [7] Prostate cancers with a Gleason score ≤ 6 usually have rather good prognoses.

  3. Prostate cancer - Wikipedia

    en.wikipedia.org/wiki/Prostate_cancer

    The lowest possible Gleason score of 6 represents a biopsy most similar to healthy prostate; the highest Gleason score of 10 represents the most severely cancerous. [note 1] Gleason scores are commonly grouped into "Gleason grade groups", which predict disease prognosis: a Gleason score of 6 is Gleason grade group 1 (best prognosis). A score of ...

  4. Donald Gleason - Wikipedia

    en.wikipedia.org/wiki/Donald_Gleason

    Thus, any given patient could have a score of between two and ten——the higher the score, the more aggressive the cancer, and the lower the chance of survival. Gleason found the score directly related to survival rates in a study of 270 patients, which was the basis of his journal report.

  5. Prostate cancer staging - Wikipedia

    en.wikipedia.org/wiki/Prostate_cancer_staging

    For prostate cancer, cell morphology is graded based on the Gleason grading system. [citation needed] Of note, this system of describing tumors as "well-", "moderately-", and "poorly-" differentiated based on Gleason score of 2–4, 5–6, and 7–10, respectively, persists in SEER and other databases but is generally outdated. In recent years ...

  6. Active surveillance of prostate cancer - Wikipedia

    en.wikipedia.org/wiki/Active_surveillance_of...

    The rate of death from prostate cancer at 10 years for men age 65–74 years with moderately differentiated cancers (Gleason score 5–7) diagnosed with screening (in the prostate cancer screening era) and pre prostate cancer screening eras (without screening) were from 2-6%, and from 15 to 23%, respectively.

  7. Survival analysis - Wikipedia

    en.wikipedia.org/wiki/Survival_analysis

    gleason: Gleason grade (3-10) The survival tree produced by the analysis is shown in the figure. Survival tree for prostate cancer data set. Each branch in the tree indicates a split on the value of a variable. For example, the root of the tree splits subjects with grade < 2.5 versus subjects with grade 2.5 or greater.

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