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Vegetable capsules, introduced in 1989, [5] are made from cellulose, a structural component in plants. The main ingredient of vegetarian capsules is hydroxypropyl methyl cellulose. In the 21st century, gelatin capsules are more broadly used than vegetarian capsules because the cost of production is lower. [citation needed]
A softgel is an oral dosage form for medicine in the form of a specialized capsule. They consist of a shell, usually gelatin based, surrounding a liquid fill. Softgel shells are a combination of gelatin , water , opacifier and a plasticiser such as glycerin or sorbitol .
Gelatin is used as a binder in match heads [39] and sandpaper. [40] Cosmetics may contain a non-gelling variant of gelatin under the name hydrolyzed collagen (hydrolysate). Gelatin was first used as an external surface sizing for paper in 1337 and continued as a dominant sizing agent of all European papers through the mid-nineteenth century. [41]
It is used primarily for gel capsules and as stabilizers for vaccines. [26] Non-animal derived alternatives to gelatin include pectin as a gelling agent or cellulose for creating capsules. [27] Lactose is derived from cow's milk and is a frequently used filler or binder in tablets and capsules. [28]
In the 1800s, sugar coating and gelatin coating were invented, as were gelatin capsules. [ 1 ] In 1843, the British painter and inventor William Brockedon was granted a patent for a machine capable of "Shaping Pills, Lozenges, and Black Lead by Pressure in Dies".
Ratanavaraporn hopes to see silk fibroin used in many more drug delivery systems to help patients across Thailand and internationally — and with that, give Thai silk farmers another revenue stream.
Gelatin is generally made from boiling bones or animal hides. That, in turn, breaks down collagen -- which is a protein. Then, that collagen cools and re-forms into -- ta-da! -- gelatin.
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