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The disorder has been named after Leo Ritter von Zombusch, who first described two cases of a brother and a sister in 1910. [7] The patients experienced patterns of redness and pustule formation over several years, often associated with use of topical medications. [2]
Generalized pustular psoriasis (GPP) is also known as (von Zumbusch) acute generalized pustular psoriasis in acute cases, and as impetigo herpetiformis during pregnancy. [3] [5] GPP is a rare and severe form of psoriasis that may require hospitalization. This form of psoriasis is characterized by an acute onset of numerous pustules on top of ...
Generalized pustular psoriasis (GPP) is a rare type of psoriasis that can present in a variety of forms. [1] Unlike the most general and common forms of psoriasis, GPP usually covers the entire body and with pus-filled blisters rather than plaques. GPP can present at any age, but is rarer in young children.
Pustulosis palmaris et plantaris is a chronic recurrent pustular dermatosis (that is, a pustulosis or pustular psoriasis) localized on the palms and soles only, characterized histologically by intraepidermal pustules filled with neutrophils. [2]: 411, 628 [3]: 204 It can occur as part of the SAPHO syndrome. [4]
The history of psoriasis is littered with treatments of dubious effectiveness and high toxicity. In the 18th and 19th centuries, Fowler's solution, which contains a poisonous and carcinogenic arsenic compound, was used by dermatologists as a treatment for psoriasis. [134] Mercury was also used for psoriasis treatment during this time. [134]
Pustular psoriasis is still primarily treated with systemic corticosteroids, which have been used for many years. [13] If a patient is not responding to corticosteroids , cyclosporine may be a useful medication. [ 14 ]
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