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Aciclovir risks causing resistance to antiviral agents, and in 1% to 10% of cases can cause unpleasant side effects. [19] Aciclovir taken by mouth does not appear to decrease the risk of pain after shingles. [20] In those with herpes of the eye, aciclovir may be more effective and safer than idoxuridine. [21]
Brivudine is used for the treatment of herpes zoster in adult patients. It is taken orally once daily, in contrast to aciclovir, valaciclovir and other antivirals. [1] A study has found that it is more effective than aciclovir, but this has been disputed because of a possible conflict of interest on part of the study authors.
Cefdinir, sold under the brand name Omnicef among others, is an antibiotic used to treat pneumonia, otitis media, strep throat, and cellulitis. [1] It is a less preferred option for pneumonia, otitis media, and strep throat which may be used in those with a severe penicillin allergy. [1]
More severe side effects are hallucinations, sleeplessness and depression. [12] Recommended dosage for efavirenz/emtricitabine/tenofovir is one tablet at or before bedtime. Side effects can be reduced if it is taken on an empty stomach. People with kidney or liver problems can take one tablet by mouth once a day.
Common side effects include headache, tiredness, trouble sleeping, abdominal pain, weight loss, and rash. [5] Serious side effects may include high blood lactate levels and enlargement of the liver. [7] Use of this medication during pregnancy does not appear to harm the fetus, but this has not been well studied. [1]
Erdosteine is a molecule with mucolytic activity. Structurally it is a thioether derivative with two thioether groups. [1] These two functional organosulfur groups contained in the molecule are released following first-pass metabolism with the conversion of erdosteine into its pharmacologically active metabolite Met-I.
Amenamevir (trade name Amenalief) is an antiviral drug used for the treatment of shingles (herpes zoster). It acts as an inhibitor of the zoster virus's helicase–primase complex. [1] [2] Amenamevir was approved in Japan for the treatment of shingles in 2017. [3]
Bictegravir was found to be less drug resistant than other drugs in the same class. [ 16 ] Emtricitabine (FTC) is a nucleoside reverse transcriptase inhibitor (NRTI) that is a synthetic fluoro derivative of thiacytidine.