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Dengue vaccine is a vaccine used to prevent dengue fever in humans. [9] Development of dengue vaccines began in the 1920s but was hindered by the need to create immunity against all four dengue serotypes. [10] As of 2023, there are two commercially available vaccines, sold under the brand names Dengvaxia and Qdenga. [11] [12]
NS1 antigen test (nonstructural protein 1) is a test for dengue, introduced in 2006. It allows rapid detection on the first day of fever, before antibodies appear some 5 or more days later. [ 1 ] It has been adopted for use in some 40 nations.
In May 2024, TAK-003 became the second dengue vaccine to be prequalified by the World Health Organization (WHO). [51] This live-attenuated vaccine, developed by Takeda is similar to the Dengvaxia vaccine in the fact that it contains a weakened version of the four variants of dengue virus. The difference between the two vaccines is the TAK-003 ...
As of December 2015, there is no commercially available vaccine for dengue fever. [50] One that is partially effective is predicted to become available in Mexico, the Philippines, and Brazil in early 2016. [4] [50] It received approval in December 2015. [4] The vaccine is produced by Sanofi and goes by the brand name Dengvaxia. [51]
These laboratory tests are only of diagnostic value during the acute phase of the illness with the exception of serology. Tests for dengue virus-specific antibodies, types IgG and IgM, can be useful in confirming a diagnosis in the later stages of the infection. Both IgG and IgM are produced after 5–7 days.
In April 2023, the National Administration of Drugs, Food and Medical Technology (ANMAT) gave the green light to the use of the tetravalent vaccine TAK-003 known as Qdenga, developed by the Japanese laboratory Takeda Pharmaceutical Company, making it the only vaccine approved to date. to combat dengue in Argentina. [22] This vaccine is based on ...
In those outbreaks; dengue virus-2 was the infecting serotype. 205 cases of dengue hemorrhagic fever and dengue shock syndrome occurred during the 1997 outbreak, all in people older than 15 years. All but three of these cases were demonstrated to have been previously infected by dengue virus-1 during the first outbreak. [ 49 ]
Dengue virus (DENV) is the cause of dengue fever.It is a mosquito-borne, single positive-stranded RNA virus of the family Flaviviridae; genus Flavivirus. [1] [2] Four serotypes of the virus have been found, and a reported fifth has yet to be confirmed, [3] [4] [5] all of which can cause the full spectrum of disease. [1]