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Levmetamfetamine, also known as l-desoxyephedrine or levomethamphetamine, and commonly sold under the brand name Vicks VapoInhaler among others, is an optical isomer of methamphetamine primarily used as a topical nasal decongestant. [2] It is used to treat nasal congestion from allergies and the common cold. [7]
An experimental nasal spray has helped clear toxic protein buildups in the brains of mouse models of Alzheimer's. Its developers believe the spray may help delay Alzheimer's by at least a decade.
Prolonged use of these types of sprays can damage the delicate mucous membranes in the nose. This causes increased inflammation, an effect known as rhinitis medicamentosa or the rebound effect. Decongestant nasal sprays are advised for short-term use only, preferably 5 to 7 days at maximum. Some doctors advise to use them 3 days at maximum.
The nasal spray prevents the glands in the nose from producing large amounts of fluid. [5] [6] It is used to treat rhinorrhea (runny nose) caused by allergic rhinitis, nonallergic rhinitis, [5] and the common cold. [7] [2] It is used by metered-dose manual pump spray. Onset of action is within an hour. [7]
Ainslie says one of the things that makes nasal spray options so exciting is the ease of delivery — which can be a lifesaver in an emergency like an opioid overdose or an allergic reaction.
Exposure to cold air can trigger a runny nose in some people. [6] Gustatory rhinitis Spicy and pungent food may in some people produce rhinorrhea, nasal stuffiness, lacrimation, sweating and flushing of face. It can be relieved by ipratropium bromide nasal spray (an anticholinergic), a few minutes before a meal. [7] Honeymoon rhinitis
First-generation antihistamine drugs such as diphenhydramine cause drowsiness, while second- and third-generation antihistamines such as fexofenadine and loratadine are less likely to. [52] [53] Pseudoephedrine is also indicated for vasomotor rhinitis. It is used only when nasal congestion is present and can be used with antihistamines.
Azelastine, sold under the brand name Astelin among others, is a H 1 receptor-blocking medication primarily used as a nasal spray to treat allergic rhinitis (hay fever) and as eye drops for allergic conjunctivitis. [5] [6] Other uses may include asthma and skin rashes for which it is taken by mouth. [7]