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A dried cannabis flower. The short-term effects of cannabis are caused by many chemical compounds in the cannabis plant, including 113 [clarification needed] different cannabinoids, such as tetrahydrocannabinol, and 120 terpenes, [1] which allow its drug to have various psychological and physiological effects on the human body.
Opiorphin is an endogenous chemical compound first isolated from human saliva. Initial research with mice shows the compound has a painkilling effect greater than that of morphine . [ 2 ] It works by stopping the normal breakup of enkephalins , natural pain-killing opioids in the spinal cord .
A 2021 review found little effect of using non-inhaled cannabis to relieve chronic pain. [8] According to a 2019 systematic review, there have been inconsistent results of using cannabis for neuropathic pain, spasms associated with multiple sclerosis and pain from rheumatic disorders, but was not effective treating chronic cancer pain.
Though, causes of variations in the TPS enzymes are still unknown. Monoterpenes myrcene and sesquiterpenes β-caryophyllene (binds to the human CB2 cannabinoids receptor) and α-humulene are the most common terpene compounds, and are present in most varieties of cannabis strains. The lack of exact standards makes it sometimes difficult for ...
Both the immense pain and the duration of the sting are due to the effects of poneratoxin. [5] In addition to the notorious pain, symptoms of stings from bullet ants (as well as stings from other ants of the genus Paraponera as well as the genus Dinoponera) include fever, cold sweats, nausea, vomiting, lymphadenopathy and cardiac arrhythmias.
Studies conflict on whether long-term cannabis use causes persistent structural changes in humans. Twin studies have shown no significant difference between users and non-users in twin pairs, [ 70 ] but other studies have demonstrated that chronic use affects white matter and hippocampal volume in the brains of healthy (non-psychotic) patients ...
Effects include euphoria, hallucinations, changes in perception, a distorted sense of time, [19] and perceived spiritual experiences. It can also cause adverse reactions such as nausea and panic attacks. Imagery in cave paintings and rock art of modern-day Algeria and Spain suggests that human use of psilocybin mushrooms predates recorded ...
The clinical presentation in humans ranges from a mild and uncomplicated diarrhea to a hemorrhagic colitis with severe abdominal pain. Serotype O157:H7 may trigger an infectious dose with 100 bacterial cells or fewer; other strain such as 104:H4 has also caused an outbreak in Germany 2011.