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Typhoid vaccines are vaccines that prevent typhoid fever. [1] [2] [3] Several types are widely available: typhoid conjugate vaccine (TCV), Ty21a (a live oral vaccine) and Vi capsular polysaccharide vaccine (ViPS) (an injectable subunit vaccine). They are about 30 to 70% effective in the first two years, depending on the specific vaccine in ...
The Vi capsular polysaccharide vaccine (or ViCPS) is a typhoid vaccine recommended by the World Health Organization for the prevention of typhoid (another is Ty21a).The vaccine was first licensed in the US in 1994 and is made from the purified Vi capsular polysaccharide from the Ty2 Salmonella Typhi strain; it is a subunit vaccine.
Ty21a is a live attenuated bacterial vaccine that protects against typhoid.First licensed in Europe in 1983 and in the United States in 1989, it is an orally administered, live-attenuated Ty2 strain of S. Typhi in which multiple genes, including the genes responsible for the production of Vi, have been deleted so as to render it harmless but nevertheless immunogenic.
Although vaccination programs for typhoid have proven effective, they alone cannot eliminate typhoid fever. [39] Combining vaccines with public-health efforts is the only proven way to control this disease. [39] Since the 1990s, the WHO has recommended two typhoid fever vaccines. The ViPS vaccine is given by injection, and the Ty21a by capsules.
The DTaP is a combination vaccine that covers three diseases; Diphtheria, Pertussis and Tetanus. The DTaP vaccine is given as a 5-shot series at 2, 4, and 6 months, the fourth between 12 and 15 months, and the last between 4–6 years. A booster is recommended to be given between 11 and 12 years of age and is called Tdap. [2]
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The ACIP was established in March 1964 by the US Surgeon General to assist in the prevention and control of communicable diseases, [2] it recommends licensed new vaccines to be incorporated into the routine immunization schedule, recommends vaccine formulations, and reviews older vaccines to consider revising its recommendations.
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