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  2. D-value (microbiology) - Wikipedia

    en.wikipedia.org/wiki/D-value_(microbiology)

    The half life is actually roughly 30% (log 10 2 ≈ 30.103%) of the D-value, so if D = 10 minutes, the number of living microorganisms will be halved in about 3 minutes. Generally, each lot of a sterilization-resistant organism will have its own specific D-value. Determining a D-value requires an experiment, but only gives the D-value under the ...

  3. Anprolene - Wikipedia

    en.wikipedia.org/wiki/Anprolene

    Anprolene is a registered trade name for ethylene oxide that belongs to Andersen Sterilizers.. Harold Willids Andersen invented Anprolene in 1967 and used plastic bags and small ampoules, hence, substantially less ethylene oxide (EtO) than traditional chamber type sterilizers which employ tanks of EtO.

  4. Geobacillus stearothermophilus - Wikipedia

    en.wikipedia.org/wiki/Geobacillus_stearothermophilus

    Geobacillus stearothermophilus (previously Bacillus stearothermophilus) [1] [2] is a rod-shaped, Gram-positive bacterium and a member of the phylum Bacillota. The bacterium is a thermophile and is widely distributed in soil, hot springs, ocean sediment, and is a cause of spoilage in food products. It will grow within a temperature range of 30 ...

  5. Central sterile services department - Wikipedia

    en.wikipedia.org/wiki/Central_sterile_services...

    Sterile dental instruments from hospital central supply (barcoded label indicating sterilization date, expiry date and contents). The central sterile services department (CSSD), also called sterile processing department (SPD), sterile processing, central supply department (CSD), or central supply, is an integrated place in hospitals and other health care facilities that performs sterilization ...

  6. Sterilant gas monitoring - Wikipedia

    en.wikipedia.org/wiki/Sterilant_Gas_Monitoring

    The odor threshold for these gases is above the PELs and for ethylene oxide it is 500 ppm, approaching that of the IDLH. [1] Odor is thus inadequate as a monitoring technique. Continuous gas monitors are used as part of an overall safety program to provide a prompt alert to nearby workers in the event that there is a leak of the sterilant gas ...

  7. Sterilization (microbiology) - Wikipedia

    en.wikipedia.org/wiki/Sterilization_(microbiology)

    Ethylene oxide treatment is the most common chemical sterilization method, used for approximately 70% of total sterilizations, and for over 50% of all disposable medical devices. [ 26 ] [ 27 ] Ethylene oxide treatment is generally carried out between 30 and 60 °C (86 and 140 °F) with relative humidity above 30% and a gas concentration between ...

  8. Validation (drug manufacture) - Wikipedia

    en.wikipedia.org/wiki/Validation_(drug_manufacture)

    Validation is a requirement of food, drug and pharmaceutical regulating agencies such as the US FDA and their good manufacturing practices guidelines. Since a wide variety of procedures, processes, and activities need to be validated, the field of validation is divided into a number of subsections including the following:

  9. Cleaning validation - Wikipedia

    en.wikipedia.org/wiki/Cleaning_validation

    Cleaning validation is the methodology used to assure that a cleaning process removes chemical and microbial residues of the active, inactive or detergent ingredients of the product manufactured in a piece of equipment, the cleaning aids utilized in the cleaning process and the microbial attributes.

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