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Cholecystitis causes the gallbladder to become distended and firm. Distension can lead to decreased blood flow to the gallbladder, causing tissue death and eventually gangrene. [13] Once tissue has died, the gallbladder is at greatly increased risk of rupture (perforation), which can cause sharp pain.
Gangrene is a type of tissue death caused by a lack of blood supply. [4] Symptoms may include a change in skin color to red or black, numbness, swelling, pain, skin breakdown, and coolness. [1] The feet and hands are most commonly affected. [1] If the gangrene is caused by an infectious agent, it may present with a fever or sepsis. [1]
Gallbladder diseases are diseases involving the gallbladder and is closely linked to biliary disease, with the most common cause being gallstones (cholelithiasis). [1] [2]The gallbladder is designed to aid in the digestion of fats by concentrating and storing the bile made in the liver and transferring it through the biliary tract to the digestive system through bile ducts that connect the ...
Non-gangrenous ischemic colitis, which comprises the vast majority of cases, is associated with a mortality rate of approximately 6%. [34] However, the minority of patients who develop gangrene as a result of colonic ischemia have a mortality rate of 50–75% with surgical treatment; the mortality rate is almost 100% without surgical intervention.
Only about 25 to 40% of bile duct injuries are detected intraoperatively. A biliary stricture, leak, or obstruction may be the injury's outward manifestation. A history of gallbladder empyema or gangrenous cholecystitis as reasons for cholecystectomy should raise the possibility of biliary injury. If the bile duct injury is not recognized right ...
Bowel infarction or gangrenous bowel represents an irreversible injury to the intestine resulting from insufficient blood flow. It is considered a medical emergency because it can quickly result in life-threatening infection and death. [ 1 ]
The prognosis depends on prompt diagnosis (less than 12–24 hours and before gangrene) [37] and the underlying cause: [38] venous thrombosis: 32% mortality; arterial embolism: 54% mortality; arterial thrombosis: 77% mortality; non-occlusive ischemia: 73% mortality. In the case of prompt diagnosis and therapy, acute intestinal ischemia can be ...
Courvoisier's sign occurs due to the gradual (chronic) nature of the obstruction caused by cancer (e.g. pancreatic, often located in pancreatic head, cholangiocarcinoma, etc.), which gradually causes biliary back-pressure and gradually distends the gallbladder over time, without causing acute damage, thus without causing pain.