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It is a protein that in humans is encoded by gene ABCC11. [3] [4] [5] The gene is responsible for determination of human cerumen type (wet or dry ear wax) and presence of underarm osmidrosis (odor associated with sweat caused by apocrine secretion), and is associated with colostrum secretion. [6]
The ABCC11 gene determines axillary body odor and the type of earwax. [6] [31] [32] [33] The loss of a functional ABCC11 gene is caused by a 538G>A single-nucleotide polymorphism, resulting in a loss of body odor in people who are specifically homozygous for it.
Body odor encompasses axillary (underarm) odor and foot odor. [1] It is caused by a combination of sweat gland secretions and normal skin microflora. [1] In addition, androstane steroids and the ABCC11 transporter are essential for most axillary odor. [1] [2] Body odor is a complex phenomenon, with numerous compounds and catalysts involved in ...
Nguyen explained that body odor is primarily associated with apocrine sweat glands, found in the armpit and groin areas. ... For those without the mutation in the ABCC11 gene, protein in those ...
Some people may carry a gene variation that helps them avoid body odor. Some people don't have body odor, even without deodorant. Here's why — and what we can learn from them.
Sweat and body odor are typically thought to go hand in hand, but experts say it's a little more complicated than that. Sweat alone doesn't have a smell, according to Harvard Health.
The majority of East Asians have the ABCC11 gene (80-95%), which greatly reduces body odor and codes for dry-type earwax. [29] It is believed that this reduction in body odor may be an adaptation to colder climates by ancient Northeast Asian ancestors, although this is not definitively proven. [30]
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