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Splenic infarction is a condition in which blood flow supply to the spleen is compromised, [1] leading to partial or complete infarction (tissue death due to oxygen shortage) in the organ. [2] Splenic infarction occurs when the splenic artery or one of its branches are occluded, for example by a blood clot. [3]
Splenic artery aneurysms are rare, but still the third most common abdominal aneurysm, after aneurysms of the abdominal aorta and iliac arteries. [2] [3] They may occur in pregnant women in the third trimester and rupture carries a maternal mortality of greater than 50% and a fetal mortality of 70 to 90%.
Even after surgical treatment, the mortality rate remains as high as 39.4%. [13] Most cases occur during infancy when the mortality rates are at their highest. Vein of Galen malformations are a relatively unknown condition, attributed to the rareness of the malformations.
Symptoms can occur when the aneurysm pushes on a structure in the brain. Symptoms will depend on whether an aneurysm has ruptured or not. There may be no symptoms present at all until the aneurysm ruptures. [21] For an aneurysm that has not ruptured the following symptoms can occur: [citation needed] Fatigue; Loss of perception; Loss of balance
In other cases, a similarly developed pseudoaneurysm ("false aneurysm") may burst, sometimes resulting in the death of the patient. Also, blood clots may form on the inside of ventricular aneurysms, and form embolisms. If such a clot escapes from the aneurysm, it will be moved in the circulation throughout the body.
Blunt splenic trauma most often occurs in automobile accident victims, in which it is a leading cause of internal bleeding. However, any type of major impact directed to the spleen may cause splenic trauma. This can happen in bicycling accidents, when the handlebar is forced into the left subcostal margin, and into the spleen.
A splenic injury, which includes a ruptured spleen, is any injury to the spleen. The rupture of a normal spleen can be caused by trauma , such as a traffic collision . Signs and symptoms
Splenomegaly can result in hematologic disturbances and abdominal pain and can increase the risk for splenic rupture, which also causes spleen pain, from blunt trauma, resulting in life-threatening internal bleeding. [2] Many conditions can cause splenomegaly, such as various infections, liver disease, and cancer. [2]