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Creutzfeldt–Jakob disease (CJD), also known as subacute spongiform encephalopathy or neurocognitive disorder due to prion disease, is a fatal neurodegenerative disease. [ 4 ] [ 1 ] Early symptoms include memory problems, behavioral changes, poor coordination, and visual disturbances. [ 4 ]
The CJDSS was created in 1998 (along with a slew of other OECD national reporting systems [4] [5] [6]) "in response to the widespread outbreak of vCJD in the United Kingdom", [7] and "is a research project that relies on direct CJD reporting by all neurologists, neurosurgeons, neuropathologists, geriatricians, and infectious disease physicians to the" PHAC.
A child must also exhibit four other symptoms in order to be clinically diagnosed. However, according to the Omnigraphics Health References Series: Depression Sourcebook, Third Edition, [35] a more calculated evaluation must be given by a medical or mental health professional such as a physiologist or psychiatrist. Following the bases of ...
The Children's Depression Inventory (CDI and CDI2) is a psychological assessment that rates the severity of symptoms related to depression or dysthymic disorder in children and adolescents. [1] The CDI is a 27-item scale that is self-rated and symptom-oriented. [ 1 ]
Fatal insomnia is an extremely rare neurodegenerative prion disease that results in trouble sleeping as its hallmark symptom. [2] The majority of cases are familial (fatal familial insomnia [FFI]), stemming from a mutation in the PRNP gene, with the remainder of cases occurring sporadically (sporadic fatal insomnia [sFI]).
vCJD is a separate condition from classic Creutzfeldt–Jakob disease (though both are caused by PrP prions). [9] Both classic and variant CJD are subtypes of Creutzfeldt–Jakob disease. There are three main categories of CJD disease: sporadic CJD, hereditary CJD, and acquired CJD, with variant CJD being in the acquired group along with ...
Women and children usually consumed the brain, the organ in which infectious prions were most concentrated, thus allowing for transmission of kuru. The disease was therefore more prevalent among women and children. The epidemic likely started when a villager developed sporadic Creutzfeldt–Jakob disease and died. When villagers ate the brain ...
The Center for Epidemiologic Studies Depression Scale for Children (CES-DC) is a modified version of the Center for Epidemiologic Studies Depression Scale. This measure assesses both depressive symptoms as well as symptom improvement in a wide range of children and adolescents, ages 6–17. [ 3 ]