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Vitamin C, an antioxidant, is required to make the building blocks for collagen, carnitine, and catecholamines, and assists the intestines in the absorption of iron from foods. [2] [4] [5] Diagnosis is typically based on outward appearance, X-rays, and improvement after treatment. [2] Treatment is with vitamin C supplements taken by mouth. [1]
The condition is associated with sailors who weren't eating fruit and vegetables — but it's more common than you'd think.
Vitamin C has a definitive role in treating scurvy, which is a disease caused by vitamin C deficiency. Beyond that, a role for vitamin C as prevention or treatment for various diseases is disputed, with reviews often reporting conflicting results.
The design for a medical study in 1743 that was never carried out may have inspired James Lind’s groundbreaking clinical trial that determined the treatment for scurvy. A 1747 study found the ...
The historic importance of vitamin C deficiency relates to occurrence on long sea-going voyages, when the ship food supplies had no good source of the vitamin. Deficiency results in scurvy when plasma concentrations fall below 0.2 mg/dL, whereas the normal plasma concentration range is 0.4 to 1.5 mg/dL.
Scurvy is a disease caused by a vitamin C deficiency, but in Lind's day, the concept of vitamins was unknown. Vitamin C is necessary for healthy connective tissue. In 1740 the catastrophic result of then-Commodore George Anson's circumnavigation attracted much attention in Europe; out of 1900 men, 1400 died, most of them allegedly from scurvy ...
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