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Options for prevention include allopurinol, febuxostat, and probenecid. Lowering uric acid levels can cure the disease. [7] Treatment of associated health problems is also important. [7] Lifestyle interventions have been poorly studied. [90] It is unclear whether dietary supplements have an effect in people with gout. [92]
Gout is a serious and painful form of arthritis that occurs when there is too much uric acid in the blood. “It is a very common form of arthritis,” says rheumatologist Dr. Orrin Troum. “Pain ...
Unless high blood levels of uric acid are determined in a clinical laboratory, hyperuricemia may not cause noticeable symptoms in most people. [5] Development of gout – which is a painful, short-term disorder – is the most common consequence of hyperuricemia, which causes deposition of uric acid crystals usually in joints of the extremities, but may also induce formation of kidney stones ...
Low uric acid (hypouricemia) can have numerous causes. Low dietary zinc intakes cause lower uric acid levels. This effect can be even more pronounced in women taking oral contraceptive medication. [59] Sevelamer, a drug indicated for prevention of hyperphosphataemia in people with chronic kidney failure, can significantly reduce serum uric acid ...
The symptoms caused by the buildup of uric acid (gout and kidney symptoms) respond well to treatment with medications such as allopurinol that reduce the levels of uric acid in the blood. The mental deficits and self-mutilating behavior do not respond well to treatment. There is no cure, but many affected people live to adulthood.
Colchicine is typically prescribed to mitigate or prevent the onset of gout, or its continuing symptoms and pain, using a low-dose prescription of 0.6 to 1.2 mg per day, or a high-dose amount of up to 4.8 mg in the first 6 hours of a gout episode. [13][25] With an oral dose of 0.6 mg, peak blood levels occur within one to two hours. [50] For ...
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