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A tensilon test, also called an edrophonium test, is a pharmacological test used for the diagnosis of certain neural diseases, especially myasthenia gravis. [1] It is also used to distinguish a myasthenic crisis from a cholinergic crisis in individuals undergoing treatment for myasthenia gravis.
Edrophonium is a readily reversible acetylcholinesterase inhibitor. It prevents breakdown of the neurotransmitter acetylcholine and acts by competitively inhibiting the enzyme acetylcholinesterase , mainly at the neuromuscular junction .
Pyridostigmine is a medication used to treat myasthenia gravis [1] and underactive bladder. [2] It is also used together with atropine to end the effects of neuromuscular blocking medication of the non-depolarizing type. [3] It is also used off-label to treat some forms of Postural orthostatic tachycardia syndrome.
In a retrospective review of almost 32,000 people, etomidate, when used for the induction of anaesthesia, was associated 2.5-fold increase in the risk of dying compared with those given propofol. [37] People given etomidate also had significantly greater odds of having cardiovascular morbidity and significantly longer hospital stay. [37]
Pancuronium is used with general anesthesia in surgery for muscle relaxation and as an aid to intubation or ventilation. It does not have sedative or analgesic effects.. Side-effects include moderately raised heart rate and thereby arterial pressure and cardiac output, excessive salivation, apnea and respiratory depression, rashes, flushing, and sweating.
A growing number of prominent companies have scaled back or set aside the diversity, equity and inclusion initiatives that much of corporate America endorsed following the protests that ...
Acetylcholinesterase inhibitors are one of two types of cholinesterase inhibitors; the other being butyryl-cholinesterase inhibitors. [2] Acetylcholinesterase is the primary member of the cholinesterase enzyme family. [3] Acetylcholinesterase inhibitors are classified as reversible, irreversible, or quasi-irreversible (also called pseudo ...
A comprehensive review of clinical trials involving semaglutide — specifically the 2.4 mg dose used for Wegovy — highlighted that one of the drug’s significant advantages is its ...