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Mohs surgery is the gold standard method for obtaining complete margin control during removal of a skin cancer (complete circumferential peripheral and deep margin assessment - CCPDMA) using frozen section histology. [1] CCPDMA or Mohs surgery allows for the removal of a skin cancer with very narrow surgical margin and a high cure rate.
Appropriate use criteria (AUC), sometimes referred to as appropriateness criteria (AC), specify when it is appropriate to perform a medical procedure or service. An "appropriate" procedure is one for which the expected health benefits exceed the expected health risks by a wide margin.
Connolly, Ad Hoc Task Force, et al. "AAD/ACMS/ASDSA/ASMS 2012 appropriate use criteria for Mohs micrographic surgery: A report of the American Academy of Dermatology, American College of Mohs Surgery, American Society for Dermatologic Surgery Association, and the American Society for Mohs Surgery." Dermatologic Surgery 38.10 (2012): 1582-1603.
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Surgery to remove the basal-cell carcinoma affected area and the surrounding skin is thought to be the most effective treatment. [40] A disadvantage with standard surgical excision is a reported higher recurrence rate of basal-cell cancers of the face, [ 41 ] especially around the eyelids, [ 42 ] nose, and facial structures. [ 43 ]
Women over 40 should get breast cancer screenings every other year, according to the U.S. Preventive Services Task Force. But some doctors think scans should be annual.
The American Cancer Society guidelines say that women ages 40 through 44 should have the option to start screening annually. Between the ages of 45 and 54, people should definitely get screened ...
For example, gentamicin is an antibiotic that can be nephrotoxic (kidney damaging) and ototoxic (hearing damaging); measurement of gentamicin through concentrations in a patient's plasma and calculation of the AUC is used to guide the dosage of this drug. [3] AUC becomes useful for knowing the average concentration over a time interval, AUC/t.