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Contemporary research in neurobiology (a branch of science that deals with the anatomy, [9] physiology, and pathology of nervous system) of addiction points to genetics as a major contributing factor to addiction vulnerability. It has been estimated that 40–60% of the vulnerability to developing an addiction is due to genetics.
Blum markets a genetic test, the Genetic Addiction Risk Score (GARS), through his company IGENE LLC in partnership with Dominion Diagnostics, [19] [17] [20] through LifeGen, Inc., where he is chairman of the board and chief scientific officer, [21] and via Geneus Health for whom he also acts chief scientific officer and chairman. [22]
The Addiction Severity Index (ASI) is used to assess the severity of patient's addiction and analyse the need of treatment which has been in use for more than 2 decades since its publication in 1992. It is used in a variety of settings such as clinics, mental health services in the US, the Indian Health Service and several European countries ...
The impact factor relates to a specific time period; it is possible to calculate it for any desired period. For example, the JCR also includes a five-year impact factor, which is calculated by dividing the number of citations to the journal in a given year by the number of articles published in that journal in the previous five years. [14] [15]
In genetics, a polygenic score (PGS) is a number that summarizes the estimated effect of many genetic variants on an individual's phenotype. The PGS is also called the polygenic index ( PGI ) or genome-wide score ; in the context of disease risk, it is called a polygenic risk score ( PRS or PR score [ 1 ] ) or genetic risk score .
Substance dependence, also known as drug dependence, is a biopsychological situation whereby an individual's functionality is dependent on the necessitated re-consumption of a psychoactive substance because of an adaptive state that has developed within the individual from psychoactive substance consumption that results in the experience of withdrawal and that necessitates the re-consumption ...
Addiction Biology is a quarterly peer-reviewed scientific journal covering research on substance abuse. It is one of two journals published on behalf of the Society for the Study of Addiction to Alcohol and other Drugs. The major focus of Addiction Biology is on neuroscience contributions from animal experimentation and clinical point of views.
LSD also received a 0.3 score for physical addiction. More disturbingly, these are averaged numbers, so, seeing as how many of the psychiatrists surely voted 0 in the above categories, the one or more addiction psychiatrists rating LSD as intravenously harmful or physically addictive must have rated the substance much higher than 0.3 in each ...