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Postherpetic neuralgia (PHN) is neuropathic pain that occurs due to damage to a peripheral nerve caused by the reactivation of the varicella zoster virus (herpes zoster, also known as shingles). PHN is defined as pain in a dermatomal distribution that lasts for at least 90 days after an outbreak of herpes zoster. [ 1 ]
The vaccine reduced rates of persistent, severe pain after shingles by 66% in people who contracted shingles despite vaccination. [59] Vaccine efficacy was maintained through four years of follow-up. [59] It has been recommended that people with primary or acquired immunodeficiency should not receive the live vaccine. [59]
8. Shingles. Shingles is caused by the varicella zoster virus (the same one that leads to chickenpox), according to the CDC. After you recover from chickenpox, the virus stays inactive in your ...
A zoster vaccine is a vaccine that reduces the incidence of herpes zoster (shingles), a disease caused by reactivation of the varicella zoster virus, which is also responsible for chickenpox. [ 8 ] Shingles provokes a painful rash with blisters, and can be followed by chronic pain ( postherpetic neuralgia ), as well as other complications.
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If you're a healthy adult age 50 or above, you should get vaccinated against shingles, medical experts say. The vaccine they recommend is Shingrix. With its more than 90 percent success in ...
After it subsides, it stays dormant in nerve cells in the body. It may reactivate under conditions of physiological stress or if the immune system is suppressed in any way (for example during an illness or undergoing chemotherapy), resulting in herpes zoster , also known as shingles or Ramsay Hunt syndrome when facial paralysis in involved.
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