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Causality: Models, Reasoning, and Inference (2000; [1] updated 2009 [2]) is a book by Judea Pearl. [3] It is an exposition and analysis of causality. [4] [5] It is considered to have been instrumental in laying the foundations of the modern debate on causal inference in several fields including statistics, computer science and epidemiology. [6]
Causal inference is the process of determining the independent, actual effect of a particular phenomenon that is a component of a larger system. The main difference between causal inference and inference of association is that causal inference analyzes the response of an effect variable when a cause of the effect variable is changed.
The preliminary research leading up to a randomized clinical trial (RCT) of a drug or biologic has been termed "plausibility building". This involves the gathering and analysis of biochemical, tissue or animal data which are eventually found to point to a mechanism of action or to demonstrate the desired biological effect.
Causal analysis is the field of experimental design and statistical analysis pertaining to establishing cause and effect. [1] [2] Exploratory causal analysis (ECA), also known as data causality or causal discovery [3] is the use of statistical algorithms to infer associations in observed data sets that are potentially causal under strict assumptions.
The study of causality extends from ancient philosophy to contemporary neuropsychology; assumptions about the nature of causality may be shown to be functions of a previous event preceding a later one. The first known protoscientific study of cause and effect occurred in Aristotle's Physics. [1] Causal inference is an example of causal reasoning.
Causal analysis is the field of experimental design and statistics pertaining to establishing cause and effect. [1] Typically it involves establishing four elements: correlation, sequence in time (that is, causes must occur before their proposed effect), a plausible physical or information-theoretical mechanism for an observed effect to follow from a possible cause, and eliminating the ...
Causality, within sociology, has been the subject of epistemological debates, particularly concerning the external validity of research findings; one factor driving the tenuous nature of causation within social research is the wide variety of potential "causes" that can be attributed to a particular phenomena.
Causal research, is the investigation of (research into) cause-relationships. [1] [2] [3] To determine causality, variation in the variable presumed to influence the difference in another variable(s) must be detected, and then the variations from the other variable(s) must be calculated (s).