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Serotonin syndrome (SS) is a group of symptoms that may occur with the use of certain serotonergic medications or drugs. [1] The symptoms can range from mild to severe, and are potentially fatal. [ 4 ] [ 5 ] [ 2 ] Symptoms in mild cases include high blood pressure and a fast heart rate ; usually without a fever . [ 2 ]
A typical SSRI dosage alone won’t cause serotonin syndrome, but taking this type of antidepressant with other medications that increase serotonin levels can. SSRIs and pregnancy.
Haloperidol, sold under the brand name Haldol among others, is a typical antipsychotic medication. [9] Haloperidol is used in the treatment of schizophrenia , tics in Tourette syndrome , mania in bipolar disorder , delirium , agitation, acute psychosis , and hallucinations from alcohol withdrawal .
This is a list of drugs and substances that are known or suspected to cause Stevens–Johnson syndrome This is a dynamic list and may never be able to satisfy particular standards for completeness. You can help by adding missing items with reliable sources .
Fenclonine (para-chlorophenylalanine; PCPA) An inhibitor of serotonin synthesis that has been used in the treatment of carcinoid syndrome. Feverfew [2] Is a herb traditionally used for migraines (contains parthenolide [3]). Reserpine Depletes serotonin stores in the brain, heart, and many other organs and has been used in hypertension and psychosis
5-HT 3 receptor antagonists or serotonin antagonists were first introduced in the early 1990s, and they have become the most widely used antiemetic drugs in chemotherapy. [29] They have also been proven safe and effective for treatment of postoperative nausea and vomiting. [30]
Medication Brand name Class Vehicle Dosage T max t 1/2 single t 1/2 multiple logP c Ref Aripiprazole lauroxil: Aristada: Atypical: Water a: 441–1064 mg/4–8 weeks: 24–35 days? 54–57 days: 7.9–10.0: Aripiprazole monohydrate: Abilify Maintena: Atypical: Water a: 300–400 mg/4 weeks: 7 days? 30–47 days: 4.9–5.2: Bromperidol decanoate ...
Other drugs that have been reported to potentiate rather than inhibit the effects of serotonergic psychedelics include lithium, reserpine, pindolol, and methysergide. [6] Pindolol, a beta blocker and serotonin 5-HT 1A receptor antagonist, has been reported to potentiate the hallucinogenic effects of DMT by 2- to 3-fold in humans. [33] [34]