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2,3-Methylenedioxymethamphetamine (2,3-MDMA), also known as ORTHO-MDMA, is a positional isomer of the recreational drug 3,4-MDMA (commonly known as Ecstasy or Molly). [1] It is a monoamine transporter (MAT) substrate and inhibitor similarly to 3,4-MDMA. [2]
Serotonin depletion following MDMA use can cause depression in subsequent days. In some cases, depressive symptoms persist for longer periods. [8] Some studies indicate repeated recreational use of ecstasy is associated with depression and anxiety, even after quitting the drug. [95] Depression is one of the main reasons for cessation of use. [8]
At the center, Molly receives the opioid antagonist shot, but due to her having drugs in her system, she goes into acute withdrawal, and they rush to the hospital. Four months later, Molly is still living with Deb, visits her children regularly, is getting ready for her next shot, and is on her way to recovery.
Substance-related disorders, also known as substance use disorders, are a type of mental disorder that affects a person's brain and behavior, leading to their inability to control their use of substances like legal or illegal drugs, alcohol, or medications.
The opioid epidemic took hold in the U.S. in the 1990s. Percocet, OxyContin and Opana became commonplace wherever chronic pain met a chronic lack of access to quality health care, especially in Appalachia. The Centers for Disease Control and Prevention calls the prescription opioid epidemic the worst of its kind in U.S. history.
Diabetes is very common. The Centers for Disease Control and Prevention (CDC) notes that 38.4 million people in the United States are currently living with diabetes. That’s 11.6 percent of the ...
The mean age at presentation is thirty-seven years with a reported range of nineteen to sixty-four years. The mean age of onset since diagnosis of diabetes is fifteen years. The female:male ratio is 1.3:1. Other diabetic complications such as nephropathy, neuropathy, retinopathy and hypertension are usually present. Its major symptom is the ...
Substance intoxication may often accompany a substance use disorder (SUD); if persistent substance-related problems exist, SUD is the preferred diagnosis. [ 5 ] The term "intoxication" in common use most often refers to alcohol intoxication, or drug addiction usually opioids consisting of an overdose; resulting in death.