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Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). [1] Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke , heart failure, kidney failure and myocardial infarction .
More research is needed on these oral antihypertensive drugs to determine which one is the best for most pregnant women. [30] Additionally, a study done in 2023 demonstrated that treatment of patients with oral diuretic furosemide, a loop diuretic, may decrease the length of hypertension postpartum.
Use in pregnancy may harm the baby and use when breastfeeding is not recommended. [10] It is an angiotensin II receptor antagonist and works by blocking the effects of angiotensin II. [5] Irbesartan was patented in 1990, and approved for medical use in 1997. [11] It is available as a generic medication. [9]
Pregnancy or preeclampsia. Problems with your adrenal glands. ... This sounds like a lot, but your healthcare provider can recommend the best antihypertensive medication for you, depending on your ...
Trandolapril is teratogenic (US: pregnancy category D) and can cause birth defects and even death of the developing fetus. The highest risk to the fetus is during the second and third trimesters. When pregnancy is detected, trandolapril should be discontinued as soon as possible. Trandolapril should not be administered to nursing mothers ...
When methyldopa was first introduced, it was the mainstay of antihypertensive treatment, but its use has declined on account of relatively severe adverse side effects, with increased use of other safer and more tolerable agents such as alpha blockers, beta blockers, and calcium channel blockers.
The antihypertensive activity of hydralazine was discovered by scientists at Ciba, who were trying to discover drugs to treat malaria; it was initially called C-5968 and 1-hydrazinophthalazine; Ciba's patent application was filed in 1945 and issued in 1949, [19] [20] [21] and the first scientific publications of its blood pressure-lowering ...
The antihypertensive characteristics of prazosin make it a second-line choice for the treatment of high blood pressure. [11] Prazosin is also useful in treating urinary hesitancy associated with benign prostatic hyperplasia, blocking α 1-adrenergic receptors, which control constriction of both the prostate and urethra. Although not a first ...