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Prurigo nodularis (PN), also known as nodular prurigo, is a skin disorder characterized by pruritic , nodular lesions, which commonly appear on the trunk, arms and legs. [1] Patients often present with multiple excoriated nodules caused by chronic scratching.
[19] [20] Clinically, the diagnosis of any particular skin condition is made by gathering pertinent information regarding the presenting skin lesion(s), including the location (such as arms, head, legs), symptoms (pruritus, pain), duration (acute or chronic), arrangement (solitary, generalized, annular, linear), morphology (macules, papules ...
Prurigo is a reactive skin condition distinguished by numerous, isolated itchy papules. [1] The word "prurigo" comes from the Latin word pruire, which meaning itching. Ferdinand von Hebra coined the term "prurigo" in Vienna in 1850 to describe papules and nodules that had severe pruritus . [ 2 ]
Pruritus ani is the irritation of the skin at the exit of the rectum, known as the anus, causing the desire to scratch. [1] The intensity of anal itching increases from moisture, [ 2 ] pressure, and rubbing caused by clothing and sitting.
An itch (also known as pruritus) is a sensation that causes a strong desire or reflex to scratch. [1] Itches have resisted many attempts to be classified as any one type of sensory experience. Itches have many similarities to pain , and while both are unpleasant sensory experiences, their behavioral response patterns are different.
Dryness, heat, cold, stress, and showering all exacerbate pruritus. Patients with this condition frequently have skin devoid of noticeable lesions. But in addition to xerosis, skin lesions like excoriation, crusts, impetigo, and prurigo nodularis may also develop as a result of repeated scratching. [4]
Chronic scratching of lesions can cause thickening or lichenification of the skin or prurigo nodularis (generalized nodules that are severely itchy). [ 34 ] Another factor in the barrier failure and immunological dysregulation in people with atopic dermatitis may be due to decreases in tight junction protein Claudin-1 .
Scalp pruritus is an itchiness of the scalp, particularly common in elderly people. [ 1 ] : 56–57 Scalp pruritus is sometimes very unpleasant because itch and pain sensations share common nerve pathways.
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