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Prurigo nodularis (PN), also known as nodular prurigo, is a skin disorder characterized by pruritic , nodular lesions, which commonly appear on the trunk, arms and legs. [1] Patients often present with multiple excoriated nodules caused by chronic scratching.
Pruritus, commonly known as itchiness, is a sensation exclusive to the skin, and characteristic of many skin conditions. [95] [96] Adult blaschkitis; Aquadynia; Aquagenic pruritus; Biliary pruritus; Cholestatic pruritus; Drug-induced pruritus; Hydroxyethyl starch-induced pruritus; Lichen simplex chronicus (neurodermatitis) Lichen simplex ...
Prurigo is a reactive skin condition distinguished by numerous, isolated itchy papules. [1] The word "prurigo" comes from the Latin word pruire, which meaning itching. Ferdinand von Hebra coined the term "prurigo" in Vienna in 1850 to describe papules and nodules that had severe pruritus . [ 2 ]
Lichen simplex chronicus (LSC) is thick leathery skin with exaggerated skin markings caused by sudden itching and excessive rubbing and scratching. [1] It generally results in small bumps, patches, scratch marks and scale. [1]
Dupilumab is the first treatment for prurigo nodularis approved by the FDA. [10] Prurigo nodularis is a rare skin disease that causes hard, itchy lumps (nodules) to form on the skin. [ 10 ]
Dryness, heat, cold, stress, and showering all exacerbate pruritus. Patients with this condition frequently have skin devoid of noticeable lesions. But in addition to xerosis, skin lesions like excoriation, crusts, impetigo, and prurigo nodularis may also develop as a result of repeated scratching. [4]
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