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Patiromer was generally well tolerated in studies. Side effects that occurred in more than 2% of patients included in clinical trials were mainly gastro-intestinal problems such as constipation, diarrhea, nausea, and flatulence, and also hypomagnesemia (low levels of magnesium in the blood) in 5% of patients, because patiromer binds magnesium in the gut as well.
Potassium binders are medications that bind potassium ions in the gastrointestinal tract, thereby preventing its intestinal absorption. This category formerly consisted solely of polystyrene sulfonate, a polyanionic resin attached to a cation, administered either orally or by retention enema to patients who are at risk of developing hyperkalaemia (abnormal high serum potassium levels).
Polystyrene sulfonates are a group of medications used to treat high blood potassium. [1] Effects generally take hours to days. [1] They are also used to remove potassium, calcium, and sodium from solutions in technical applications.
Other approved potassium binders in the United States include patiromer and sodium polystyrene sulfonate. [14] Hyperkalemia, particularly if severe, is a marker for an increased risk of death. [15] However, there is disagreement regarding whether a modestly elevated levels directly causes problems.
A powder is a dry solid composed of many very fine particles that may flow freely when shaken or tilted. Powders are a special sub-class of granular materials , although the terms powder and granular are sometimes used to distinguish separate classes of material.
Perimeter, the company behind Phos-Chek, has advised in the past cleaning the powder off as soon as it is safe to do so. "The longer the retardant dries, the more difficult it is to remove ...
Dry chemical powder is used on all classes of fires. Dry chemical powder puts out the fire by coating the burning material with a thin layer of dust, thereby separating the fuel from the oxygen in the air. The powder also works to interrupt the chemical reaction of fire, so these extinguishers are extremely effective at putting out the fire.
Itching powder was created from Mucuna pruriens in the early-19th century as a cure for lost feeling in the epidermis. When a person would lose feeling on their skin in conditions such as paralysis, the powder (mixed with lard to form an ointment) was used as a local stimulant believed to treat the condition. [9] [10]