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Gastric ulcers may develop; it is unclear if they are the causes or the consequences. Intestinal metaplasia typically begins in response to chronic mucosal injury in the antrum and may extend to the body. Gastric mucosa cells change to resemble intestinal mucosa and may even assume absorptive characteristics.
Esophageal inlet patches are well defined areas of mucosa which resemble stomach tissue and are pink or salmon colored. [2] The mucosal surface of an esophageal inlet patch is typically flat, [3] but may be slightly raised or slightly depressed.
For example, heartburn is a symptom in lymphocytic esophagitis, and proton pump inhibitors, which reduce acidity in the stomach, are consequently used for treatment. With respect to treatment of inflammation, steroids that are topical and coat the lining of the esophagus, such as budesonide have been used to treat the condition, in one German ...
Esophagitis can be asymptomatic; or can cause epigastric and/or substernal burning pain, especially when lying down or straining; and can make swallowing difficult . The most common cause of esophagitis is the reverse flow of acid from the stomach into the lower esophagus: gastroesophageal reflux disease (GERD). [2]
The usual appearance of portal hypertensive gastropathy on endoscopy is a mosaic-like or reticular pattern in the mucosa. Red spots may or may not be present. The pattern is usually seen throughout the stomach. [2] A similar pattern can be seen with a related condition called gastric antral vascular ectasia (GAVE), or watermelon stomach.
Ulcers cause breaks in the mucosa and cause erosion of the sub-mucosa. Zollinger-Ellison syndrome Gastrin levels increase due to tumors, which cause an increase in the gastric fold size. [7] Ménétrier's disease The mucosa pits are in excess causing thickening of the folds. [7] Carcinoma Helicobacter pylori infection Causes inflammation of the ...
The gastric mucosa is the mucous membrane layer of the stomach, which contains the gastric pits, to which the gastric glands empty. In humans, it is about one mm ...
An obsolete treatment is vagotomy ("highly selective vagotomy"), the surgical removal of vagus nerve branches that innervate the stomach lining. This treatment has been largely replaced by medication. Vagotomy by itself tended to worsen contraction of the pyloric sphincter of the stomach, and delayed stomach emptying.