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An oocyte (/ ˈ oʊ ə s aɪ t /, oöcyte, or ovocyte is a female gametocyte or germ cell involved in reproduction. In other words, it is an immature ovum, or egg cell. An oocyte is produced in a female fetus in the ovary during female gametogenesis. The female germ cells produce a primordial germ cell (PGC), which then undergoes mitosis ...
A germ cell is any cell that gives rise to the gametes of an organism that reproduces sexually. In many animals, the germ cells originate in the primitive streak and migrate via the gut of an embryo to the developing gonads. There, they undergo meiosis, followed by cellular differentiation into mature gametes, either eggs or sperm.
The development and maturation of sex cells also takes place during meiosis. Gametogenesis is also the process of formation in male and female gametes that occur in the gonads (ovary and testis). Both male and female produce gametes. Male gametocytes are called spermatocytes and female gametocytes are called oocytes.
In the mouse, the great majority of differentially expressed genes in PGCs from embryonic day 9.5 to 13.5, when most genes are demethylated, are upregulated in both male and female PGCs. [26] Following erasure of DNA methylation marks in mouse PGCs, male and female germ cells undergo new methylation at different time points during gametogenesis.
After female (XX) germ cells collect in the undifferentiated gonads, the up-regulation of Stra8 is required for germ cell differentiation into an oogonium and eventually enter meiosis. One major factor that contributes to the up-regulation of Stra8 , is the initiation of the β-Catenin signaling pathway via RSPO1, which is also responsible for ...
Germ cells are specified early in development [4] and can only differentiate into gametes. [5] The segregation of germ cells is often determined by the species, with some undergoing preformation, where the germ cells are determined by maternally inherited factors before or immediately after fertilisation, and others undergoing epigenesis, where the germ cell lineage is determined from ...
In 2004, considerable evidence was provided for the existence of germline stem cells in adult mouse ovaries capable of generating oocytes to form new follicles. [11] [12] [13] Questions exist about cell-sorting techniques used to isolate the OSCs, [14] and some researchers prefer the less-conclusive term "female germline stem cells" to "OSCs". [15]
The egg cell or ovum (pl.: ova) is the female reproductive cell, or gamete, [1] in most anisogamous organisms (organisms that reproduce sexually with a larger, female gamete and a smaller, male one). The term is used when the female gamete is not capable of movement (non- motile ).