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Cancer is a complex, multifactorial disease. [2] Carcinogenesis is linked with DNA mutations, chromosomal translocations, dysfunctional proteins, and aberrant cell cycle regulators. [1] Cancer alters the DNA of cells and the mutated genetic material is passed on to daughter cells, resulting in neoplasms. [2]
A dog with degenerative myelopathy often stands with its legs close together and may not correct an unusual foot position due to a lack of conscious proprioception. Canine degenerative myelopathy, also known as chronic degenerative radiculomyelopathy, is an incurable, progressive disease of the canine spinal cord that is similar in many ways to amyotrophic lateral sclerosis (ALS).
Emanuel syndrome, also known as derivative 22 syndrome, or der(22) syndrome, is a rare disorder associated with multiple congenital anomalies, including profound intellectual disability, preauricular skin tagsor pits, and conotruncalheart defects. [1][2]It can occur in offspring of carriers of the constitutional chromosomal translocation t(11 ...
Multiple myeloma (MM), also known as plasma cell myeloma and simply myeloma, is a cancer of plasma cells, a type of white blood cell that normally produces antibodies. [ 6 ] Often, no symptoms are noticed initially. [ 10 ] As it progresses, bone pain, anemia, renal insufficiency, and infections may occur. [ 10 ]
Deaths. 147,100 (2015) [ 5 ] Acute myeloid leukemia (AML) is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal cells that build up in the bone marrow and blood and interfere with normal blood cell production. [ 1 ] Symptoms may include feeling tired, shortness of breath, easy bruising and bleeding, and ...
Chromosome abnormality. A chromosomal abnormality, chromosomal anomaly, chromosomal aberration, chromosomal mutation, or chromosomal disorder is a missing, extra, or irregular portion of chromosomal DNA. [1][2] These can occur in the form of numerical abnormalities, where there is an atypical number of chromosomes, or as structural ...
Chromosomal Mutation. Cri du chat syndrome is a rare genetic disorder due to a partial chromosome deletion on chromosome 5. [ 1 ] Its name is a French term ("cat-cry" or " call of the cat ") referring to the characteristic cat-like cry of affected children (sound sample [1]). [ 2 ] It was first described by Jérôme Lejeune in 1963. [ 3 ]
If any worrying clinical signs such as weight loss, diarrhea, vomiting, lethargy or jaundice are noted, speak to your vet straight away. An early diagnosis and prompt treatment can often improve ...