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  2. Lisdexamfetamine - Wikipedia

    en.wikipedia.org/wiki/Lisdexamfetamine

    Lisdexamfetamine is a substituted amphetamine with an amide linkage formed by the condensation of dextroamphetamine with the carboxylate group of the essential amino acid L -lysine. [ 19 ] The reaction occurs with retention of stereochemistry, so the product lisdexamfetamine exists as a single stereoisomer.

  3. Pyrrolysine - Wikipedia

    en.wikipedia.org/wiki/Pyrrolysine

    Pyrrolysine is synthesized in vivo by joining two molecules of L -lysine. One molecule of lysine is first converted to (3 R)-3-methyl- D -ornithine, which is then ligated to a second lysine. An NH 2 group is eliminated, followed by cyclization and dehydration step to yield L -pyrrolysine.

  4. Lysine - Wikipedia

    en.wikipedia.org/wiki/Lysine

    Lysine (symbol Lys or K) [2] is an α-amino acid that is a precursor to many proteins.It contains an α-amino group (which is in the protonated −NH + 3 form when dissolved in water), an α-carboxylic acid group (which is in the deprotonated −COO − form when dissolved in water), and a side chain lysyl ((CH 2) 4 NH 2), classifying it as a basic, charged (at physiological pH), aliphatic ...

  5. Lipoic acid - Wikipedia

    en.wikipedia.org/wiki/Lipoic_acid

    Digestive proteolytic enzymes cleave the R-lipoyllysine residue from the mitochondrial enzyme complexes derived from food but are unable to cleave the lipoic acid-L-lysine amide bond. [23] Both synthetic lipoamide and (R)-lipoyl-L-lysine are rapidly cleaved by serum lipoamidases, which release free (R)-lipoic acid and either L-lysine or ammonia ...

  6. 6-Diazo-5-oxo-L-norleucine - Wikipedia

    en.wikipedia.org/wiki/6-Diazo-5-oxo-L-norleucine

    N Y (what is this?) (verify) 6-Diazo-5-oxo-L-norleucine (DON) is a glutamine antagonist, which was isolated originally from Streptomyces in a sample of Peruvian soil. This diazo compound is biosynthesized from lysine by three enzymes in bacteria. [2] It is one of the most famous non-proteinogenic amino acid and was characterized in 1956 by ...

  7. Ibuprofen - Wikipedia

    en.wikipedia.org/wiki/Ibuprofen

    Ibuprofen lysine is sold for rapid pain relief; [97] given in the form of its lysine salt, absorption is much quicker (35 minutes for the salt compared to 90–120 minutes for ibuprofen). However, a clinical trial with 351 participants in 2020, funded by Sanofi, found no significant difference between ibuprofen and ibuprofen lysine concerning ...

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