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Freckles are clusters of concentrated melaninized cells which are most easily visible on people with a fair complexion.Freckles do not have an increased number of the melanin-producing cells, or melanocytes, but instead have melanocytes that overproduce melanin granules (melanosomes) changing the coloration of the outer skin cells (keratinocytes).
Freckles and moles are formed where there is a localized concentration of melanin in the skin. They are highly associated with pale skin. They are highly associated with pale skin. Nicotine has an affinity for melanin-containing tissues because of its precursor function in melanin synthesis or its irreversible binding of melanin.
This is an accepted version of this page This is the latest accepted revision, reviewed on 28 January 2025. "Skin pigmentation" redirects here. For animal skin pigmentation, see Biological pigment. Extended Coloured family from South Africa showing some spectrum of human skin coloration Human skin color ranges from the darkest brown to the lightest hues. Differences in skin color among ...
Eumelanin is the dominant form of melanin found in human skin. Eumelanin protects tissues and DNA from radiation damage by UV light. Melanin is produced in specialized cells called melanocytes, which are found in the lowest level of the epidermis. [85] Melanin is produced inside small membrane-bound packages called melanosomes.
It’s also a powerful treatment for melasma since it inhibits the production of pigment in the skin and the transfer of melanin between cells, meaning it can reduce and help prevent dark spots ...
The actual skin colour of different humans is affected by many substances, although the single most important substance determining human skin colour is the pigment melanin. Melanin is produced within the skin in cells called melanocytes and it is the main determinant of the skin colour of darker-skinned humans.
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Melanin is a dark pigment primarily responsible for skin color. Once synthesized, melanin is contained in special organelles called melanosomes which can be transported to nearby keratinocytes to induce pigmentation. Thus darker skin tones have more melanosomes present than lighter skin tones.