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Replacement chainrings must be chosen with a bolt-hole count and spacing that matches the spider. Chainrings designed for use with multi-chainring crank arms may have ramps or pins to aid in shifting. The middle chainring, in the case of a triple crankset, usually has the most shaping to aid in shifting up and down.
As straight-bladed Mayo scissors are also used for cutting sutures, they are also referred to as "suture scissors". Curved-bladed Mayo scissors allow deeper penetration into the wound than the type with straight blades. The curved style of Mayo scissor is used to cut thick tissues such as those found in the uterus, muscles, breast, and foot.
Because of the possibility of the chain shifting past the smallest inner chainring, especially when the inner chainring is very small, even on bikes adjusted by professional race mechanics, and the problems such misshifts can cause, a small after-market of add-on products, called chain deflectors, exists to help prevent them from occurring.
The blade is made of non-rustproof carbon steel, blue-plastered by hand and finely forged from the base to the tip of the knife. The 90 mm (3.5 in) long blade shows patina (dark spots) caused by decades of use. It can easily be sharpened to a shaving sharp edge. Carbon steel is a popular choice for rough-use knives and cheaper options.
Osymetric is a French make of ovoid bicycle chainring which has a non-circular shape whose angle is tailored to the pedal stroke of the individual cyclist. These were designed by engineer Jean-Louis Talo who claims that this improves cycling performance.
Beneficial side effects are less common; some examples, in many cases of side-effects that ultimately gained regulatory approval as intended effects, are: Bevacizumab ( Avastin ), used to slow the growth of blood vessels, has been used against dry age-related macular degeneration , as well as macular edema from diseases such as diabetic ...
Less common side effects of bicalutamide monotherapy in men include sexual dysfunction, depression, fatigue, weakness, and anemia. Bicalutamide is well tolerated and has few side effects in women. General side effects of bicalutamide that may occur in either sex include diarrhea, constipation, abdominal pain, nausea, dry skin, itching, and rash.
Type A: augmented pharmacological effects, which are dose-dependent and predictable [5]; Type A reactions, which constitute approximately 80% of adverse drug reactions, are usually a consequence of the drug's primary pharmacological effect (e.g., bleeding when using the anticoagulant warfarin) or a low therapeutic index of the drug (e.g., nausea from digoxin), and they are therefore predictable.
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