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Acute interstitial pneumonitis (also known as acute interstitial pneumonia) is a rare, severe lung disease that usually affects otherwise healthy individuals. There is no known cause or cure. Acute interstitial pneumonitis is often categorized as both an interstitial lung disease and a form of acute respiratory distress syndrome (ARDS).
Usual interstitial pneumonia (UIP) is a form of lung disease characterized by progressive scarring of both lungs. [1] The scarring ( pulmonary fibrosis ) involves the pulmonary interstitium (the supporting framework of the lung).
Interstitial lung disease affects gas flow in the alveoli The alveoli Micrograph of usual interstitial pneumonia (UIP). UIP is the most common pattern of idiopathic interstitial pneumonia (a type of interstitial lung disease) and usually represents idiopathic pulmonary fibrosis .
It may also be classified by the area of the lung affected: lobar, bronchial pneumonia and acute interstitial pneumonia; [42] or by the causative organism. [82] Pneumonia in children may additionally be classified based on signs and symptoms as non-severe, severe, or very severe. [83]
The presence of bronchocentric lymphohistiocytic interstitial pneumonia with chronic bronchiolitis and non-necrotising granulomas coincides with pneumonitis. [ 13 ] Since pneumonitis manifests in all areas of the lungs, imaging such as chest x-rays and Computerized tomography (CT) scans are useful diagnostic tools. [ 3 ]
The acute form can be characterized by poorly formed noncaseating interstitial granulomas and mononuclear cell infiltration in a peribronchial distribution with prominent giant cells. [1] The subacute, or intermittent, form produces more well-formed noncaseating granulomas, bronchiolitis with or without organizing pneumonia , and interstitial ...
Desquamative interstitial pneumonia has a favourable prognosis and most patients improve with proper treatment. The mortality rate of DIP is between 6 and 28%. [22] The survival rate of DIP is estimated to be between 68% and 94%. Without treatment around 60% of patients get worse. Spontaneous recovery had also been reported. [16]
Idiopathic interstitial pneumonia (IIP), or noninfectious pneumonia [1] are a class of diffuse lung diseases. These diseases typically affect the pulmonary interstitium , although some also have a component affecting the airways (for instance, cryptogenic organizing pneumonitis ).
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