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Nicotine may be safer than nicotine plus the other chemicals found in cigarettes and vapes, but on its own, nicotine has been associated with detrimental health effects as well, says Bhatnagar.
Young people's brains build synapses faster than adult brains. [6] Because addiction is a form of learning, adolescents can get addicted more easily than adults. [6] The nicotine in e-cigarettes and other tobacco products can also prime the adolescent brain for addiction to other drugs such as cocaine. [51]
The LD 50 of nicotine is 50 mg/kg for rats and 3 mg/kg for mice. 0.5–1.0 mg/kg can be a lethal dosage for adult humans, and 0.1 mg/kg for children. [19] [20] However the widely used human LD 50 estimate of 0.5–1.0 mg/kg was questioned in a 2013 review, in light of several documented cases of humans surviving much higher doses; the 2013 review suggests that the lower limit causing fatal ...
The dextrorotatory form, (+)-nicotine is physiologically less active than (−)-nicotine. (−)-nicotine is more toxic than (+)-nicotine. [162] The salts of (−)-nicotine are usually dextrorotatory; this conversion between levorotatory and dextrorotatory upon protonation is common among alkaloids. [161]
Nicotine replacement therapies such as nicotine patches, gum, lozenges, inhalers and nasal spray “have also shown great efficacy” in helping people quit, says Vijayaraghavan.
The numbers can vary, but Christensen often tells patients to think of one cigarette as having 5 to 10 milligrams of nicotine each, with the actual amount inhaled probably less than that. Nicotine ...
Some (primarily in the European Union and Canada) believe in "tobacco harm reduction", with the general belief that while it should remain a goal to reduce addiction to nicotine in the population as a whole, the reduction of harm to the health of those who choose to use nicotine is more pragmatic than the desire to reduce overall nicotine ...
This is an accepted version of this page This is the latest accepted revision, reviewed on 6 February 2025. Circumstances, mechanisms, and factors of tobacco consumption on human health "Health effects of smoking" and "Dangers of smoking" redirect here. For cannabis, see Effects of cannabis. For smoking crack cocaine, see Crack cocaine § Health issues. "Smoking and health" redirects here. For ...