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For patients who require preventive therapy with symptoms such as more than 4 migraines per month or migraines lasting longer than 12 hours, first-line drugs for the prevention of migraine attacks include beta blockers, antidepressants, and anti convulsants.
Rescue treatment involves acute symptomatic control with medication. [4] Recommendations for rescue therapy of migraine include: (1) migraine-specific agents such as triptans, CGRP antagonists, or ditans for patients with severe headaches or for headaches that respond poorly to analgesics, (2) non-oral (typically nasal or injection) route of administration for patients with vomiting, (3) avoid ...
Given as pills, shots, or nasal sprays, these medications treat a migraine attack by blocking pain pathways to the brain. They include prescription drugs such as sumatriptan (Imitrex, Tosymra) and ...
Medications in the anti-calcitonin gene-related peptide, including eptinezumab, erenumab, fremanezumab, and galcanezumab, appear to decrease the frequency of migraines by one to two per month. [ 25 ] A 2006 review article by S. Modi and D. Lowder offers some general guidelines on when a physician should consider prescribing drugs for migraine ...
Naratriptan (trade names include Amerge) is a triptan drug marketed by GlaxoSmithKline and is used for the treatment of migraine headaches. It is a selective 5-HT 1 receptor subtype agonist . It was patented in 1987 and approved for medical use in 1997.
The third approved treatment, as of 2018, galcanezumab, brand name Emgality, was approved in the U.S. for use in migraines. It also interacts with the protein. [25] As of February 2020, eptinezumab (Vyepti) was approved by the FDA for the treatment of migraine via intravenous infusion as well. [26]
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Fremanezumab, sold under the brand name Ajovy, is a medication used to prevent migraines in adults. [8] [6] It is given by injection under the skin. [8] [6] The most common side effect is pain and redness at the site of injection. [8] Other side effects include allergic reactions. [8]
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