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  2. Macrocytosis: What causes it? - Mayo Clinic

    www.mayoclinic.org/macrocytosis/expert-answers/faq-20058234

    Macrocytosis isn't a specific disease, but it may indicate an underlying problem that requires medical evaluation. Common causes of macrocytosis include: Vitamin B-12 deficiency. Folate deficiency. Liver disease. Alcoholism. Hypothyroidism. A side effect of certain medications, such as those used to treat cancer, seizures and autoimmune disorders.

  3. Systemic mastocytosis - Symptoms and causes - Mayo Clinic

    www.mayoclinic.org/diseases-conditions/systemic-mastocytosis/symptoms-causes/...

    Too many mast cells can build up in the skin, liver, spleen, bone marrow or intestines. Less commonly, other organs such as the brain, heart or lungs also may be affected. Signs and symptoms of systemic mastocytosis may include: Flushing, itching or hives. Abdominal pain, diarrhea, nausea or vomiting. Anemia or bleeding disorders.

  4. Hemochromatosis - Symptoms and causes - Mayo Clinic

    www.mayoclinic.org/diseases-conditions/hemochromatosis/symptoms-causes/syc...

    Hemochromatosis (he-moe-kroe-muh-TOE-sis) causes your body to absorb too much iron from the food you eat. Excess iron is stored in your organs, especially your liver, heart and pancreas. Too much iron can lead to life-threatening conditions, such as liver disease, heart problems and diabetes. There are a few types of hemochromatosis, but the ...

  5. Thrombocytosis - Symptoms and causes - Mayo Clinic

    www.mayoclinic.org/diseases-conditions/thrombocytosis/symptoms-causes/syc-20378315

    Causes. Bone marrow is a spongy tissue inside your bones. It contains stem cells that can become red blood cells, white blood cells or platelets. Platelets stick together, helping blood to form a clot that stops bleeding when you damage a blood vessel, such as when you cut yourself. Thrombocytosis occurs when your body produces too many platelets.

  6. Myelodysplastic syndromes - Symptoms and causes - Mayo Clinic

    www.mayoclinic.org/.../myelodysplastic-syndrome/symptoms-causes/syc-20366977

    People with myelodysplastic syndromes might not experience signs and symptoms at first. In time, myelodysplastic syndromes might cause: Fatigue. Shortness of breath. Unusual paleness (pallor), which occurs due to a low red blood cell count (anemia) Easy or unusual bruising or bleeding, which occurs due to a low blood platelet count ...

  7. Systemic mastocytosis - Diagnosis and treatment - Mayo Clinic

    www.mayoclinic.org/diseases-conditions/systemic-mastocytosis/diagnosis...

    Diagnosis. To diagnose systemic mastocytosis, your doctor will likely start by reviewing your symptoms and discussing your medical history, including medications you've taken. He or she can then order tests that look for high levels of mast cells or the substances they release. Evaluation of organs affected by the condition also may be done.

  8. Drugs, Alcohol, and Other Usual Suspects in Macrocytosis -...

    www.medscape.com/viewarticle/drugs-alcohol-and-other-usual-suspects...

    The marrow is sending out a lot of younger cells that are bigger on average, and that can result in macrocytosis. Or something is causing abnormalities to the cells; it could be lipid metabolism ...

  9. Non-Hodgkin's lymphoma - Symptoms and causes - Mayo Clinic

    www.mayoclinic.org/diseases-conditions/non-hodgkins-lymphoma

    Non-Hodgkin's lymphoma is a type of cancer that begins in your lymphatic system, which is part of the body's germ-fighting immune system. In non-Hodgkin's lymphoma, white blood cells called lymphocytes grow abnormally and can form growths (tumors) throughout the body. Non-Hodgkin's lymphoma is a general category of lymphoma.

  10. Hypothyroidism: Does it cause joint pain? - Mayo Clinic

    www.mayoclinic.org/diseases-conditions/hypothyroidism/expert-answers/...

    Answer From Juan Brito Campana, M.B.B.S. For some people, hypothyroidism that hasn't been treated can lead to joint and muscle problems. Specifically, hypothyroidism may cause: Muscle aches, tenderness and stiffness. Joint pain and stiffness, particularly in the hands and knees in adults. Swelling of the small joints in the hands and feet.

  11. High red blood cell count Causes - Mayo Clinic

    www.mayoclinic.org/symptoms/high-red-blood-cell-count/basics/causes/sym-20050858

    Rarely, in some kidney cancers or after kidney transplant, the kidneys might produce too much of the hormone erythropoietin. This causes the body to make more red blood cells. Red blood cell counts also can be high in nonalcoholic fatty liver disease. Nonalcoholic fatty liver disease. Causes shown here are commonly associated with this symptom.