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Atopic dermatitis (AD), also known as atopic eczema, is a long-term type of inflammation of the skin. [2] AD is also often called simply eczema but the same term is also used to refer to dermatitis, the larger group of skin conditions. [2][5] AD results in itchy, red, swollen, and cracked skin. [2] Clear fluid may come from the affected areas ...
Atopy. Atopy is the tendency to produce an exaggerated immunoglobulin E (IgE) immune response to otherwise harmless substances in the environment. [2] Allergic diseases are clinical manifestations of such inappropriate, atopic responses. [2] Atopy may have a hereditary component, although contact with the allergen or irritant must occur before ...
In the EU, abrocitinib is indicated for the treatment of moderate-to-severe atopic dermatitis in adults who are candidates for systemic therapy. [9]In the US, abrocitinib is indicated for the treatment of people twelve years of age and older with refractory, moderate-to-severe atopic dermatitis whose disease is not adequately controlled with other systemic drug products, including biologics ...
The SCORAD ("SCORing Atopic Dermatitis") index is a clinical tool for assessing the extent of the disease, disease intensity, and subjective symptoms of atopic dermatitis. [1] It gives approximate weights of 60% to intensity and 20% each to extent and subjective symptoms. These are used to calculate a maximum total score of 103, however, the ...
Dupilumab, sold under the brand name Dupixent, is a monoclonal antibody blocking interleukin 4 and interleukin 13, used for allergic diseases such as atopic dermatitis (eczema), asthma and nasal polyps which result in chronic sinusitis. [6][7][8][4] It is also used for the treatment of eosinophilic esophagitis, [9] prurigo nodularis [10] and ...
Pimecrolimus. Pimecrolimus is an immunosuppressant drug of the calcineurin inhibitor class used in the treatment of atopic dermatitis (eczema). It is available as a topical cream. It was developed and formerly marketed by Novartis under the trade name Elidel.
October 9, 2024 at 5:43 PM. A study from the University of California Berkeley’s Institute for Research on Labor and Employment found that a California state law raised the minimum wage for fast ...
Crisaborole (chemical name: 4- [ (1-hydroxy-1,3-dihydro-2,1-benzoxaborol-5-yl)oxy]benzonitrile) is a member of the class of benzoxaboroles characterized by the presence of a boronic acid hemiester with a phenolic ether and a nitrile. [7] Crisaborole crystallizes into two polymorphs that differ in the conformation of the oxaborole ring.
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