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There are three main lab values that are commonly evaluated in relation to liver health: aspartate aminotransferase (AST), alanine transaminase (ALT) and alkaline phosphatase (ALP). AST and ALT are markers of liver cell injury.
ALT and AST are liver enzymes produced by the liver. If you have high levels of ALT and AST in your blood, it could be a sign of liver disease. The ratio of ALT to AST can help diagnose the underlying cause.
Aspartate transaminase (AST). AST is an enzyme that helps the body break down amino acids. Like ALT, AST is usually present in blood at low levels. An increase in AST levels may mean liver damage, liver disease or muscle damage. This test is sometimes referred to as SGOT. Alkaline phosphatase (ALP).
Aspartate transaminase (AST). Gamma-glutamyl transferase (GGT). If your liver is injured, it releases enzymes into your bloodstream (most commonly ALT or AST).
An AST test looks for blood levels of aspartate aminotransferase, an enzyme found mostly in the liver. Higher-than-average AST levels may be a sign of liver damage or liver disease, though there may be other causes at play.
While both are known as liver enzymes, AST is found in more parts of your body than ALT. For this reason, higher-than-normal levels of ALT tend to be a more specific indicator of liver conditions than higher-than-normal AST levels.
What does it mean if my alanine transaminase (ALT) is high? High levels of ALT in your blood can be due to damage or injury to the cells in your liver. An increased ALT level may indicate the following conditions: Alcohol-induced liver injury. Fatty liver disease (too much fat in your liver). Hepatitis (liver inflammation).
The liver function tests typically include alanine transaminase (ALT) and aspartate transaminase (AST), alkaline phosphatase (ALP), gamma-glutamyl transferase (GGT), serum bilirubin, prothrombin time (PT), the international normalized ratio (INR), total protein and albumin.
Aspartate transaminase (AST). Alkaline phosphatase (ALP). Gamma-glutamyl transpeptidase (GGT). Elevated liver enzymes might be found during routine blood testing. In most cases, liver enzymes are only mildly raised for a short time. This usually doesn't signal a chronic, serious liver problem. From Mayo Clinic to your inbox.
What level of AST and ALT is concerning? AST levels above 40 U/L can indicate liver inflammation, or damage to the heart, bones, or muscles. AST levels above 1,000 U/L may indicate...